Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Acetylajmalan esterase

Gene

AAE

Organism
Rauvolfia verticillata (Common devil-pepper) (Dissolena verticillata)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Deacetylates 17-O-acetylajmaline and 17-O-acetylnorajmaline, but is inactive toward other acetylated alkaloids.By similarity

Catalytic activityi

17-O-acetylajmaline + H2O = ajmaline + acetate.By similarity1 Publication
17-O-acetylnorajmaline + H2O = norajmaline + acetate.By similarity1 Publication

GO - Molecular functioni

  1. acetylajmaline esterase activity Source: UniProtKB-EC

GO - Biological processi

  1. alkaloid metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Alkaloid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylajmalan esteraseBy similarity (EC:3.1.1.80)
Gene namesi
Name:AAEBy similarity
OrganismiRauvolfia verticillata (Common devil-pepper) (Dissolena verticillata)
Taxonomic identifieri329875 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsGentianalesApocynaceaeRauvolfioideaeVinceaeRauvolfiinaeRauvolfia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›46›46Acetylajmalan esterasePRO_0000402568Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi39 – 391N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Family & Domainsi

Sequence similaritiesi

Belongs to the 'GDSL' lipolytic enzyme family.Sequence Analysis

Sequencei

Sequence statusi: Fragment.

P86830-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40 
NALFILGNIG NNDVNYAFPD RAIEEIRFYV PFITEAVANA TREIIR
Length:46
Mass (Da):5,242
Last modified:January 11, 2011 - v1
Checksum:i7F9778EE939B4CBD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 111 Publication
Non-terminal residuei46 – 4611 Publication

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system."
    Ruppert M., Woll J., Giritch A., Genady E., Ma X., Stockigt J.
    Planta 222:888-898(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, CATALYTIC ACTIVITY.

Entry informationi

Entry nameiAAE_RAUVE
AccessioniPrimary (citable) accession number: P86830
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: January 11, 2011
Last modified: October 1, 2014
This is version 7 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.