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P86815 (BRK5_PHYSG) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
[Ala1,Thr6]-bradykinyl-Ser,Lys,Ala,Val
OrganismPhysalaemus signifer (Girard's dwarf frog)
Taxonomic identifier364768 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaHyloideaLeptodactylidaeLeiuperinaePhysalaemus

Protein attributes

Sequence length13 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle By similarity. May target bradykinin receptors (BDKRB). UniProtKB P83058

Subcellular location

Secreted Ref.1.

Tissue specificity

Expressed by the skin glands. Ref.1

Sequence similarities

Belongs to the bradykinin-related peptide family.

Ontologies

Keywords
   Cellular componentSecreted
   Molecular functionAmphibian defense peptide
G-protein coupled receptor impairing toxin
Toxin
Vasoactive
Vasodilator
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processdefense response

Inferred from electronic annotation. Source: UniProtKB-KW

vasodilation

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Peptide1 – 1313[Ala1,Thr6]-bradykinyl-Ser,Lys,Ala,Val Ref.1
PRO_0000404690

Sequences

Sequence LengthMass (Da)Tools
P86815 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 90440D70E40CD771

FASTA131,375
        10 
APPGFTPFRS KAV 

« Hide

References

[1]"Bradykinin-related peptides in skin secretion of Physalaemus signifer (Girard, 1853) (Anura, Leiuperidae)."
Rates B., Ireno I.C., Canelas M.A., de Lima M.E., Pimenta A.M.C.
Submitted (SEP-2010) to UniProtKB
Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
Tissue: Skin secretion.

Cross-references

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR009608. Bradykinin.
[Graphical view]
PfamPF06753. Bradykinin. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBRK5_PHYSG
AccessionPrimary (citable) accession number: P86815
Entry history
Integrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 13, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families