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P86815

- BRK5_PHYSG

UniProt

P86815 - BRK5_PHYSG

Protein

[Ala1,Thr6]-bradykinyl-Ser,Lys,Ala,Val

Gene
N/A
Organism
Physalaemus signifer (Girard's dwarf frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle By similarity. May target bradykinin receptors (BDKRB).By similarity

    GO - Biological processi

    1. defense response Source: UniProtKB-KW
    2. vasodilation Source: UniProtKB-KW

    Keywords - Molecular functioni

    Amphibian defense peptide, G-protein coupled receptor impairing toxin, Toxin, Vasoactive, Vasodilator

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    [Ala1,Thr6]-bradykinyl-Ser,Lys,Ala,Val1 Publication
    OrganismiPhysalaemus signifer (Girard's dwarf frog)
    Taxonomic identifieri364768 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaHyloideaLeptodactylidaeLeiuperinaePhysalaemus

    Subcellular locationi

    Secreted 1 Publication

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Peptidei1 – 1313[Ala1,Thr6]-bradykinyl-Ser,Lys,Ala,Val1 PublicationPRO_0000404690Add
    BLAST

    Expressioni

    Tissue specificityi

    Expressed by the skin glands.1 Publication

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the bradykinin-related peptide family.Curated

    Family and domain databases

    InterProiIPR009608. Bradykinin.
    [Graphical view]
    PfamiPF06753. Bradykinin. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P86815-1 [UniParc]FASTAAdd to Basket

    « Hide

    APPGFTPFRS KAV                                           13
    Length:13
    Mass (Da):1,375
    Last modified:February 8, 2011 - v1
    Checksum:i90440D70E40CD771
    GO

    Cross-referencesi

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR009608. Bradykinin.
    [Graphical view ]
    Pfami PF06753. Bradykinin. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Bradykinin-related peptides in skin secretion of Physalaemus signifer (Girard, 1853) (Anura, Leiuperidae)."
      Rates B., Ireno I.C., Canelas M.A., de Lima M.E., Pimenta A.M.C.
      Submitted (SEP-2010) to UniProtKB
      Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
      Tissue: Skin secretion1 Publication.

    Entry informationi

    Entry nameiBRK5_PHYSG
    AccessioniPrimary (citable) accession number: P86815
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 10 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programAnimal Toxin Annotation Program
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3