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P86814

- BRK4_PHYSG

UniProt

P86814 - BRK4_PHYSG

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Protein
[Ala1,Thr6]-bradykinyl-Ser,Lys
Gene
N/A
Organism
Physalaemus signifer (Girard's dwarf frog)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle By similarity. May target bradykinin receptors (BDKRB).By similarity

GO - Biological processi

  1. defense response Source: UniProtKB-KW
  2. vasodilation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Amphibian defense peptide, G-protein coupled receptor impairing toxin, Toxin, Vasoactive, Vasodilator

Names & Taxonomyi

Protein namesi
Recommended name:
[Ala1,Thr6]-bradykinyl-Ser,Lys
OrganismiPhysalaemus signifer (Girard's dwarf frog)
Taxonomic identifieri364768 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaHyloideaLeptodactylidaeLeiuperinaePhysalaemus

Subcellular locationi

Secreted 1 Publication

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Peptidei1 – 1111[Ala1,Thr6]-bradykinyl-Ser,Lys1 Publication
PRO_0000404689Add
BLAST

Expressioni

Tissue specificityi

Expressed by the skin glands.1 Publication

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR009608. Bradykinin.
[Graphical view]
PfamiPF06753. Bradykinin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P86814-1 [UniParc]FASTAAdd to Basket

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APPGFTPFRS K                                             11
Length:11
Mass (Da):1,204
Last modified:February 8, 2011 - v1
Checksum:i3D70E40CD771A9C8
GO

Cross-referencesi

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR009608. Bradykinin.
[Graphical view ]
Pfami PF06753. Bradykinin. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Bradykinin-related peptides in skin secretion of Physalaemus signifer (Girard, 1853) (Anura, Leiuperidae)."
    Rates B., Ireno I.C., Canelas M.A., de Lima M.E., Pimenta A.M.C.
    Submitted (SEP-2010) to UniProtKB
    Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Tissue: Skin secretion.

Entry informationi

Entry nameiBRK4_PHYSG
AccessioniPrimary (citable) accession number: P86814
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 13, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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