Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Mannose-specific lectin 3

Gene
N/A
Organism
Crocus vernus (Dutch crocus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Mannose-specific lectin. Has weak agglutinating activity towards trypsin-treated erythrocytes from rabbit but not from human (By similarity).By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hemagglutinin

Keywords - Ligandi

Lectin, Mannose-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mannose-specific lectin 3
Cleaved into the following 2 chains:
OrganismiCrocus vernus (Dutch crocus)
Taxonomic identifieri87752 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaAsparagalesIridaceaeCrocus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 111111Mannose-specific lectin 3 chain 1PRO_0000395438Add
BLAST
Chaini112 – 224113Mannose-specific lectin 3 chain 2PRO_0000395439Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi30 ↔ 52PROSITE-ProRule annotation1 Publication
Disulfide bondi145 ↔ 170PROSITE-ProRule annotation1 Publication

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Heterotetramer of 2 domain 1 and 2 domain 2 chains arranged as a dimer of domain 1/domain 2 heterodimers.By similarity

Structurei

Secondary structure

1
224
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 63Combined sources
Beta strandi16 – 194Combined sources
Beta strandi22 – 265Combined sources
Beta strandi32 – 354Combined sources
Beta strandi53 – 564Combined sources
Beta strandi62 – 654Combined sources
Beta strandi73 – 797Combined sources
Beta strandi88 – 914Combined sources
Beta strandi97 – 1004Combined sources
Beta strandi102 – 1065Combined sources
Beta strandi117 – 1215Combined sources
Beta strandi125 – 1273Combined sources
Beta strandi131 – 1344Combined sources
Beta strandi137 – 1415Combined sources
Beta strandi147 – 1515Combined sources
Turni152 – 1554Combined sources
Beta strandi156 – 1605Combined sources
Beta strandi171 – 1744Combined sources
Beta strandi180 – 1834Combined sources
Beta strandi189 – 1924Combined sources
Beta strandi198 – 2003Combined sources
Beta strandi203 – 2064Combined sources
Beta strandi212 – 2154Combined sources
Beta strandi217 – 2226Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3MEZX-ray1.94A/C1-110[»]
B/D112-223[»]
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP86626.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 111110Bulb-type lectin 1PROSITE-ProRule annotationCuratedAdd
BLAST
Domaini117 – 222106Bulb-type lectin 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 bulb-type lectin domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di2.90.10.10. 2 hits.
InterProiIPR001480. Bulb-type_lectin_dom.
[Graphical view]
PfamiPF01453. B_lectin. 2 hits.
[Graphical view]
SMARTiSM00108. B_lectin. 2 hits.
[Graphical view]
SUPFAMiSSF51110. SSF51110. 2 hits.
PROSITEiPS50927. BULB_LECTIN. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P86626-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DNNVLLTGDV IHTDNQLSYE SAAFVMQGDC NLVLYNEAGG FQSNTHGRGV
60 70 80 90 100
DCTLRLNNRG QLEIHSANSN TPVWVYPRSV NTVRGNYAAT LGPDQHVTIY
110 120 130 140 150
GPAIWSTPAA ANIPRVRNVL FSSQVMYDNA QLATRDYSLV MRDDCNLVLT
160 170 180 190 200
KGSKTNIVWE SGTSGRGQHC FMRLGHSGEL DITDDRLNTV FVSNTVGQEG
210 220
DYVLILQING QAVVYGPAVW STAA
Length:224
Mass (Da):24,454
Last modified:October 19, 2011 - v3
Checksum:i94C963051247B7C6
GO

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3MEZX-ray1.94A/C1-110[»]
B/D112-223[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP86626.

Family and domain databases

Gene3Di2.90.10.10. 2 hits.
InterProiIPR001480. Bulb-type_lectin_dom.
[Graphical view]
PfamiPF01453. B_lectin. 2 hits.
[Graphical view]
SMARTiSM00108. B_lectin. 2 hits.
[Graphical view]
SUPFAMiSSF51110. SSF51110. 2 hits.
PROSITEiPS50927. BULB_LECTIN. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLEC3_CROVR
AccessioniPrimary (citable) accession number: P86626
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: October 19, 2011
Last modified: November 26, 2014
This is version 17 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

On the 2D-gel the determined pI of this protein is: 5.18, its MW is: 48 kDa.

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.