ID   PR20B_HUMAN             Reviewed;         221 AA.
AC   P86481; Q8N7V5;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   RecName: Full=Proline-rich protein 20B {ECO:0000305};
GN   Name=PRR20B {ECO:0000312|HGNC:HGNC:37220};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057823; DOI=10.1038/nature02379;
RA   Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA   Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S.,
RA   Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage A.K., Bagguley C.L.,
RA   Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P.,
RA   Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA   Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C.,
RA   Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P.,
RA   Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L.,
RA   Frankish A.G., Frankland J., French L., Garner P., Garnett J.,
RA   Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M.,
RA   Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D.,
RA   Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D.,
RA   Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S.,
RA   Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J.,
RA   Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA   Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S.,
RA   Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R.,
RA   Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W.,
RA   Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P.,
RA   Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L.,
RA   Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R.,
RA   Rogers J., Ross M.T.;
RT   "The DNA sequence and analysis of human chromosome 13.";
RL   Nature 428:522-528(2004).
CC   -!- SIMILARITY: Belongs to the PRR20 family. {ECO:0000305}.
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DR   EMBL; AL353652; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS45053.1; -.
DR   RefSeq; NP_001123876.1; NM_001130404.1.
DR   RefSeq; NP_001123877.1; NM_001130405.1.
DR   RefSeq; NP_001123878.1; NM_001130406.1.
DR   RefSeq; NP_001123879.1; NM_001130407.1.
DR   RefSeq; NP_940843.1; NM_198441.2.
DR   RefSeq; XP_016855016.1; XM_016999527.1.
DR   AlphaFoldDB; P86481; -.
DR   BioGRID; 125761; 149.
DR   BioGRID; 609637; 90.
DR   BioGRID; 609643; 90.
DR   BioGRID; 609649; 90.
DR   BioGRID; 609653; 101.
DR   iPTMnet; P86481; -.
DR   PhosphoSitePlus; P86481; -.
DR   BioMuta; PRR20B; -.
DR   DNASU; 122183; -.
DR   Ensembl; ENST00000377930.1; ENSP00000367163.1; ENSG00000204918.3.
DR   GeneID; 122183; -.
DR   GeneID; 729233; -.
DR   GeneID; 729240; -.
DR   GeneID; 729246; -.
DR   GeneID; 729250; -.
DR   KEGG; hsa:122183; -.
DR   KEGG; hsa:729233; -.
DR   KEGG; hsa:729240; -.
DR   KEGG; hsa:729246; -.
DR   KEGG; hsa:729250; -.
DR   MANE-Select; ENST00000377930.1; ENSP00000367163.1; NM_001130404.1; NP_001123876.1.
DR   AGR; HGNC:24754; -.
DR   AGR; HGNC:37220; -.
DR   AGR; HGNC:37221; -.
DR   AGR; HGNC:37222; -.
DR   AGR; HGNC:37223; -.
DR   CTD; 122183; -.
DR   CTD; 729233; -.
DR   CTD; 729240; -.
DR   CTD; 729246; -.
DR   CTD; 729250; -.
DR   GeneCards; PRR20B; -.
DR   HGNC; HGNC:37220; PRR20B.
DR   HPA; ENSG00000204918; Not detected.
DR   neXtProt; NX_P86481; -.
DR   OpenTargets; ENSG00000204919; -.
DR   PharmGKB; PA165505473; -.
DR   VEuPathDB; HostDB:ENSG00000204918; -.
DR   HOGENOM; CLU_117010_0_0_1; -.
DR   InParanoid; P86481; -.
DR   OMA; AQPEVGH; -.
DR   OrthoDB; 4737776at2759; -.
DR   PhylomeDB; P86481; -.
DR   TreeFam; TF341860; -.
DR   PathwayCommons; P86481; -.
DR   BioGRID-ORCS; 122183; 16 hits in 607 CRISPR screens.
DR   BioGRID-ORCS; 729233; 7 hits in 187 CRISPR screens.
DR   BioGRID-ORCS; 729240; 7 hits in 183 CRISPR screens.
DR   BioGRID-ORCS; 729246; 10 hits in 193 CRISPR screens.
DR   BioGRID-ORCS; 729250; 10 hits in 226 CRISPR screens.
DR   Pharos; P86481; Tdark.
DR   PRO; PR:P86481; -.
DR   Proteomes; UP000005640; Chromosome 13.
DR   RNAct; P86481; Protein.
DR   Bgee; ENSG00000204918; Expressed in primordial germ cell in gonad.
DR   InterPro; IPR031439; PRR20.
DR   PANTHER; PTHR38819; PROLINE-RICH PROTEIN 20A-RELATED; 1.
DR   PANTHER; PTHR38819:SF2; PROLINE-RICH PROTEIN 20A-RELATED; 1.
DR   Pfam; PF15708; PRR20; 1.
DR   Genevisible; P86481; HS.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..221
FT                   /note="Proline-rich protein 20B"
FT                   /id="PRO_0000393890"
FT   REGION          1..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   221 AA;  23262 MW;  E870312E6F1D607F CRC64;
     MEEPRPSKRL RSMAPNQASG GPPPEPGCCV ADPEGSVEAD GPAQPAQPAK PIAYVKPFRR
     QPPARPESPP PAERGRRRGG SRRPGRGRGR RAGPRGDAGQ RQGAEGLMAP DVHIQLDHHG
     EPGHQGEPEI TETAAFSLSE TGPPPGTVQE GPGPDVAQPE LGFQEPPAAP GPQAVDWQPV
     LTLYPCIGFR ALGDSAVLQV IQTPQGTYVQ GVPVFLTDIA Y
//