P86348 (ALPH_DEIAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Alkaline phosphatase EC=3.1.3.1
Organism	Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)
Taxonomic identifier	36307 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Lepidosauria › Squamata › Scleroglossa › Serpentes › Colubroidea › Viperidae › Crotalinae › Deinagkistrodon

Protein attributes

Sequence length	20 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Has hemorrhagic activity. Ref.1
Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate. Ref.1
Subcellular location	Secreted Ref.1.
Tissue specificity	Expressed by the venom gland. Ref.1

Ontologies

Keywords
Cellular component	Secreted
Molecular function	Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Toxin
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	alkaline phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›20	›20	Alkaline phosphatase		PRO_0000385452
Experimental info
	Non-terminal residue	20	1

Sequences

	Sequence		Length	Mass (Da)
	P86348 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: E4832D26DC22999B	FASTA	20	1,975
	10 20 DINGGGATLP QALYQTSGVL

References

[1]

"Purification and characterization of an alkaline phosphatase from Deinagkistrodon acutus snake venom." Kong T., Tang Y., Dong W., Zhong W., Cui C., Huang S. Submitted (JUL-2009) to UniProtKB Cited for: PROTEIN SEQUENCE, FUNCTION, CATALYTIC ACTIVITY, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Venom.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ALPH_DEIAC

Accession

Primary (citable) accession number: P86348

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	September 5, 2012
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Animal Toxin Annotation Program

Annotation program

Chordata Protein Annotation Program