Reviewed, UniProtKB/Swiss-Prot P86119 (PA21_OPICY)

Names and origin

Protein names	Recommended name:     Phospholipase A2 1     EC=3.1.1.4 Alternative name(s):     Phospholipase OcyPLA2_1
Organism	Opisthacanthus cayaporum (South American scorpion)
Taxonomic identifier	573324 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Chelicerata › Arachnida › Scorpiones › Iurida › Scorpionoidea › Liochelidae › Opisthacanthus

Protein attributes

Sequence length	16 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. Ref.1
Subcellular location	Secreted.
Tissue specificity	Expressed by the venom gland.
Mass spectrometry	Molecular mass is 14237 Da from positions 1 - ?. Determined by MALDI. Ref.1

Ontologies

Keywords
Biological process	Lipid degradation
Cellular component	Secreted
Molecular function	Hydrolase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	lipid catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phospholipase A2 activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›16	›16	Phospholipase A2 1		PRO_0000358859
Experimental info
	Non-terminal residue	16	1

Sequences

	Sequence		Length	Mass (Da)
	P86119-1 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: 7BB1BE9B61AB132E	FASTA	16	1,659
	10 DFTGVKFDNT IGCGKG

References

[1]

"Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum." Schwartz E.F., Camargos T.S., Zamudio F.Z., Silva L.P., Bloch C. Jr., Caixeta F., Schwartz C.A., Possani L.D. Toxicon 51:1499-1508(2008) [PubMed: 18502464] [Abstract] Cited for: PROTEIN SEQUENCE, CATALYTIC ACTIVITY, MASS SPECTROMETRY. Tissue: Venom.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

PA21_OPICY

Accession

Primary (citable) accession number: P86119

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 16, 2008
Last sequence update:	December 16, 2008
Last modified:	June 16, 2009
This is version 3 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)