P86074 (MDHM_CAPAA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Malate dehydrogenase, mitochondrial EC=1.1.1.37
Organism	Capsicum annuum var. annuum (Red pepper)
Taxonomic identifier	40321 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Capsiceae › Capsicum › Capsicum annuum

Protein attributes

Sequence length	35 AA.
Sequence status	Fragments.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	(S)-malate + NAD+ = oxaloacetate + NADH. UniProtKB P17783
Subunit structure	Homodimer By similarity. UniProtKB P17783
Subcellular location	Mitochondrion matrix By similarity UniProtKB P17783.
Sequence similarities	Belongs to the LDH/MDH superfamily. MDH type 1 family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Cellular component	Mitochondrion
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	L-malate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›35	›35	Malate dehydrogenase, mitochondrial		PRO_0000362993
Sites
	Binding site	7	1	NAD By similarity UniProtKB P61889
	Binding site	23	1	Substrate By similarity UniProtKB P61889
Experimental info
	Sequence uncertainty	3	1	L or I Ref.1
	Sequence uncertainty	4	1	F or M Ref.1
	Sequence uncertainty	6	1	I or L Ref.1
	Sequence uncertainty	10	1	I or L Ref.1
	Sequence uncertainty	12	1	K or Q Ref.1
	Sequence uncertainty	13	1	L or I Ref.1
	Sequence uncertainty	14	1	F or M Ref.1
	Sequence uncertainty	19	1	L or I Ref.1
	Sequence uncertainty	25	1	Q or K Ref.1
	Sequence uncertainty	35	1	K or Q Ref.1
	Non-adjacent residues	12 – 13	2
	Non-adjacent residues	23 – 24	2
	Non-terminal residue	1	1
	Non-terminal residue	35	1

Sequences

	Sequence		Length	Mass (Da)
	P86074 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 916AB5BAFDA5953D	FASTA	35	3,735
	10 20 30 DDLFNINAGI VKLFGVTTLD VVRTQDGGTE VVEAK

References

[1]	Almagro L., Sabater Jara A.B., Pedreno M.A. Submitted (JUL-2008) to UniProtKB Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Proteomic databases
ProMEX	P86074.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00068. MDH. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MDHM_CAPAA

Accession

Primary (citable) accession number: P86074

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	April 3, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program