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Protein

Beta-soluble NSF attachment protein

Gene

Napb

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-soluble NSF attachment proteinBy similarity
Short name:
SNAP-betaBy similarity
Alternative name(s):
N-ethylmaleimide-sensitive factor attachment protein betaBy similarity
Gene namesi
Name:NapbBy similarity
Synonyms:SnapbBy similarity
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1589649. Napb.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 297297Beta-soluble NSF attachment proteinPRO_0000349116Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineBy similarity
Modified residuei26 – 261PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiP85969.
PRIDEiP85969.

2D gel databases

World-2DPAGE0004:P85969.

PTM databases

iPTMnetiP85969.
PhosphoSiteiP85969.

Interactioni

Subunit structurei

Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2.By similarity

GO - Molecular functioni

Protein-protein interaction databases

IntActiP85969. 1 interaction.
STRINGi10116.ENSRNOP00000006329.

Structurei

3D structure databases

ProteinModelPortaliP85969.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SNAP family.Sequence analysis

Phylogenomic databases

eggNOGiKOG1586. Eukaryota.
ENOG410XPQ6. LUCA.
HOGENOMiHOG000165015.
HOVERGENiHBG001325.
InParanoidiP85969.
PhylomeDBiP85969.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR000744. NSF_attach.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PANTHERiPTHR13768. PTHR13768. 1 hit.
PRINTSiPR00448. NSFATTACHMNT.
SUPFAMiSSF48452. SSF48452. 1 hit.

Sequencei

Sequence statusi: Complete.

P85969-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNAGKEREA VQLMAEAEKR VKASHSFLRG LFGGNTRIEE ACEMYTRAAN
60 70 80 90 100
MFKMAKNWSA AGNAFCQAAK LHMQLQSKHD SATSFVDAGN AYKKADPQEA
110 120 130 140 150
INCLNAAIDI YTDMGRFTIA AKHHITIAEI YETELVDIEK AIAHYEQSAD
160 170 180 190 200
YYKGEESNSA NKCLLKVAAY AAQLEQYQKA IEIYEQVGAN TMDNPLLKYS
210 220 230 240 250
AKDYFFKAAL CHFIVDELNA KLALEKYEEM FPAFTDSREC KLLKKLLEAH
260 270 280 290
EEQNSEAYTE AVKEFDSISR LDQWLTTMLL RIKKSIQGDG EGDGDLK
Length:297
Mass (Da):33,470
Last modified:September 2, 2008 - v1
Checksum:iF7F38BC930148315
GO

Sequence cautioni

The sequence EDL95093.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH474026 Genomic DNA. Translation: EDL95093.1. Sequence problems.
UniGeneiRn.166492.

Genome annotation databases

UCSCiRGD:1589649. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH474026 Genomic DNA. Translation: EDL95093.1. Sequence problems.
UniGeneiRn.166492.

3D structure databases

ProteinModelPortaliP85969.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP85969. 1 interaction.
STRINGi10116.ENSRNOP00000006329.

PTM databases

iPTMnetiP85969.
PhosphoSiteiP85969.

2D gel databases

World-2DPAGE0004:P85969.

Proteomic databases

PaxDbiP85969.
PRIDEiP85969.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:1589649. rat.

Organism-specific databases

RGDi1589649. Napb.

Phylogenomic databases

eggNOGiKOG1586. Eukaryota.
ENOG410XPQ6. LUCA.
HOGENOMiHOG000165015.
HOVERGENiHBG001325.
InParanoidiP85969.
PhylomeDBiP85969.

Miscellaneous databases

PROiP85969.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR000744. NSF_attach.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PANTHERiPTHR13768. PTHR13768. 1 hit.
PRINTSiPR00448. NSFATTACHMNT.
SUPFAMiSSF48452. SSF48452. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Proteome profile of the mature rat olfactory bulb."
    Maurya D.K., Sundaram C.S., Bhargava P.
    Proteomics 9:2593-2599(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiSNAB_RAT
AccessioniPrimary (citable) accession number: P85969
Secondary accession number(s): A6K7C6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 6, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.