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Protein

Wasp kinin PMM1

Gene
N/A
Organism
Polistes major (Neotropical social wasp)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Induces relaxation of arterial smooth muscle, by targeting bradykinin receptors (BDKRB) (By similarity). May cause hypotension.By similarity

GO - Biological processi

  1. regulation of blood pressure Source: UniProtKB-KW
  2. response to stress Source: InterPro
  3. vasodilation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Bradykinin receptor impairing toxin, G-protein coupled receptor impairing toxin, Hypotensive agent, Toxin, Vasoactive, Vasodilator

Names & Taxonomyi

Protein namesi
Recommended name:
Wasp kinin PMM1
OrganismiPolistes major (Neotropical social wasp)
Taxonomic identifieri91420 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataVespoideaVespidaePolistinaePolistiniPolistes

Subcellular locationi

Secreted 1 Publication

GO - Cellular componenti

  1. extracellular region Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Peptidei1 – 1111Wasp kinin PMM11 PublicationPRO_0000371796Add
BLAST

Expressioni

Tissue specificityi

Expressed by the venom gland.1 Publication

Family & Domainsi

Sequence similaritiesi

Belongs to the bradykinin-related peptide family.Curated

Family and domain databases

InterProiIPR009608. Bradykinin.
[Graphical view]
PfamiPF06753. Bradykinin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P85873-1 [UniParc]FASTAAdd to Basket

« Hide

        10 
KRRPPGFTPF R
Length:11
Mass (Da):1,359
Last modified:May 5, 2009 - v1
Checksum:i33D415D6A9C86777
GO

Mass spectrometryi

Molecular mass is 1359.3 Da from positions 1 - 11. Determined by MALDI. 1 Publication

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR009608. Bradykinin.
[Graphical view]
PfamiPF06753. Bradykinin. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of three novel peptides isolated from the venom of the neotropical social wasp Polistes major major."
    Cerovsky V., Pohl J., Yang Z., Alam N., Attygalle A.B.
    J. Pept. Sci. 13:445-450(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, MASS SPECTROMETRY.
    Strain: Subsp. major1 Publication.
    Tissue: Venom1 Publication.

Entry informationi

Entry nameiBRK_POLMJ
AccessioniPrimary (citable) accession number: P85873
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 5, 2009
Last modified: October 1, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.