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Protein

Wasp kinin PMM1

Gene
N/A
Organism
Polistes major (Neotropical social wasp)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Induces relaxation of arterial smooth muscle, by targeting bradykinin receptors (BDKRB) (By similarity). May cause hypotension.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Bradykinin receptor impairing toxin, G-protein coupled receptor impairing toxin, Hypotensive agent, Toxin, Vasoactive, Vasodilator

Names & Taxonomyi

Protein namesi
Recommended name:
Wasp kinin PMM1
OrganismiPolistes major (Neotropical social wasp)
Taxonomic identifieri91420 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataVespoideaVespidaePolistinaePolistiniPolistes

Subcellular locationi

GO - Cellular componenti

  • extracellular region Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00003717961 – 11Wasp kinin PMM11 PublicationAdd BLAST11

Expressioni

Tissue specificityi

Expressed by the venom gland.1 Publication

Family & Domainsi

Sequence similaritiesi

Belongs to the bradykinin-related peptide family.Curated

Family and domain databases

InterProiIPR009608. Bradykinin.
[Graphical view]
PfamiPF06753. Bradykinin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Length:11
Mass (Da):1,359
Last modified:May 5, 2009 - v1
Checksum:i33D415D6A9C86777
GO

Mass spectrometryi

Molecular mass is 1359.3 Da from positions 1 - 11. Determined by MALDI. 1 Publication

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR009608. Bradykinin.
[Graphical view]
PfamiPF06753. Bradykinin. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBRK_POLMJ
AccessioniPrimary (citable) accession number: P85873
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 5, 2009
Last modified: October 1, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.