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P85814 (TPIS_PLAOI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Triosephosphate isomerase

Short name=TIM
EC=5.3.1.1
Alternative name(s):
Triose-phosphate isomerase
Allergen=Pla o 4
OrganismPlatanus orientalis (Oriental plane tree)
Taxonomic identifier122832 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsProtealesPlatanaceaePlatanus

Protein attributes

Sequence length86 AA.
Sequence statusFragments.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

D-glyceraldehyde 3-phosphate = glycerone phosphate. UniProtKB P04789

Pathway

Carbohydrate biosynthesis; gluconeogenesis. UniProtKB P04789

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. UniProtKB P04789

Subunit structure

Homodimer By similarity. UniProtKB P04789

Allergenic properties

Causes an allergic reaction in human. Ref.1

Sequence similarities

Belongs to the triosephosphate isomerase family.

Mass spectrometry

Molecular mass is 27074.8 Da . Determined by MALDI. Ref.1

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
Pentose shunt
   DiseaseAllergen
   Molecular functionIsomerase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

glycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiontriose-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›86›86Triosephosphate isomerase
PRO_0000343452

Sites

Active site621Proton acceptor By similarity UniProtKB P04789

Experimental info

Non-adjacent residues16 – 172
Non-adjacent residues29 – 302
Non-adjacent residues47 – 482
Non-adjacent residues56 – 572
Non-terminal residue11
Non-terminal residue861

Sequences

Sequence LengthMass (Da)Tools
P85814 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: D816B8C38C23ACA1

FASTA868,935
        10         20         30         40         50         60 
MAATSLTAPP SFSGLRASRA VVAMAGTGKG GAFTGEISVE QLKDIGRWVI LGHSERIVVA 

        70         80 
YEPVWAIGTG KVATPDQAQE VHGLCR 

« Hide

References

[1]"Identification, cloning and expression of Platanus orientalis pollen allergens."
Pazouki N.
Thesis (2008), Islamic Azad university, Iran
Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY, ALLERGEN.
Tissue: Pollen.

Cross-references

3D structure databases

ProteinModelPortalP85814.
SMRP85814. Positions 54-86.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP85814.
ProMEXP85814.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00189.
UPA00138.

Family and domain databases

Gene3D3.20.20.70. 2 hits.
InterProIPR013785. Aldolase_TIM.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view]
PANTHERPTHR21139. PTHR21139. 1 hit.
PfamPF00121. TIM. 2 hits.
[Graphical view]
SUPFAMSSF51351. SSF51351. 1 hit.
PROSITEPS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTPIS_PLAOI
AccessionPrimary (citable) accession number: P85814
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: July 1, 2008
Last modified: October 16, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Allergens

Nomenclature of allergens and list of entries