Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Kirola

Gene
N/A
Organism
Actinidia deliciosa (Kiwi)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • response to biotic stimulus Source: InterPro
  • type I hypersensitivity Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Kirola1 Publication
Alternative name(s):
Allergen: Act d 111 Publication
OrganismiActinidia deliciosa (Kiwi)
Taxonomic identifieri3627 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridsEricalesActinidiaceaeActinidia

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei5903. Act d 11.
6135. Act d 11.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 150150KirolaPRO_0000407853Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine1 Publication

Post-translational modificationi

The N-terminus is blocked.1 Publication

Keywords - PTMi

Acetylation

Structurei

Secondary structure

1
150
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 129Combined sources
Helixi17 – 259Combined sources
Helixi30 – 345Combined sources
Turni36 – 383Combined sources
Beta strandi39 – 479Combined sources
Beta strandi55 – 628Combined sources
Beta strandi65 – 7713Combined sources
Turni78 – 814Combined sources
Beta strandi82 – 909Combined sources
Helixi91 – 944Combined sources
Beta strandi96 – 10712Combined sources
Beta strandi108 – 1103Combined sources
Beta strandi112 – 12413Combined sources
Helixi131 – 14515Combined sources
Turni146 – 1483Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IGVX-ray1.50A1-150[»]
4IGWX-ray2.55A/B1-150[»]
4IGXX-ray2.35A/B/C/D1-150[»]
4IGYX-ray2.92A/B/C/D1-150[»]
4IH0X-ray1.75A1-150[»]
4IH2X-ray2.00A1-150[»]
4IHRX-ray1.60A1-150[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MLP family.Sequence analysis

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR000916. Bet_v_I/MLP.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
SMARTiSM01037. Bet_v_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P85524-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLSGKMVKQ VEILSDGIVF YEIFRYRLYL ISEMSPVNIQ GVDLLEGNWG
60 70 80 90 100
TVGSVIFFKY TIDGKEKTAK DIVEAIDEET KSVTFKIVEG DLMELYKTFI
110 120 130 140 150
IIVQVDTKGE HNSVTWTFHY EKLKEDVEEP NTLMNFCIEI TKDIETYHLK
Length:150
Mass (Da):17,404
Last modified:May 3, 2011 - v1
Checksum:iE5D429C4B5605898
GO

Mass spectrometryi

Molecular mass is 17441 Da from positions 1 - 150. Determined by MALDI. 1 Publication
Molecular mass is 17460 Da from positions 1 - 150. Determined by MALDI. Variant Thr-54.1 Publication

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti54 – 541S → T.2 Publications

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FG437290 mRNA. No translation available.
FG440357 mRNA. No translation available.
FG445803 mRNA. No translation available.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FG437290 mRNA. No translation available.
FG440357 mRNA. No translation available.
FG445803 mRNA. No translation available.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IGVX-ray1.50A1-150[»]
4IGWX-ray2.55A/B1-150[»]
4IGXX-ray2.35A/B/C/D1-150[»]
4IGYX-ray2.92A/B/C/D1-150[»]
4IH0X-ray1.75A1-150[»]
4IH2X-ray2.00A1-150[»]
4IHRX-ray1.60A1-150[»]
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei5903. Act d 11.
6135. Act d 11.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR000916. Bet_v_I/MLP.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
SMARTiSM01037. Bet_v_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening."
    Crowhurst R.N., Gleave A.P., MacRae E.A., Ampomah-Dwamena C., Atkinson R.G., Beuning L.L., Bulley S.M., Chagne D., Marsh K.B., Matich A.J., Montefiori M., Newcomb R.D., Schaffer R.J., Usadel B., Allan A.C., Boldingh H.L., Bowen J.H., Davy M.W.
    , Eckloff R., Ferguson A.R., Fraser L.G., Gera E., Hellens R.P., Janssen B.J., Klages K., Lo K.R., MacDiarmid R.M., Nain B., McNeilage M.A., Rassam M., Richardson A.C., Rikkerink E.H., Ross G.S., Schroder R., Snowden K.C., Souleyre E.J., Templeton M.D., Walton E.F., Wang D., Wang M.Y., Wang Y.Y., Wood M., Wu R., Yauk Y.K., Laing W.A.
    BMC Genomics 9:351-351(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT THR-54.
    Tissue: FruitCurated.
  2. "Kiwifruit Act d 11 is the first member of the ripening-related protein family identified as an allergen."
    D'Avino R., Bernardi M.L., Wallner M., Palazzo P., Camardella L., Tuppo L., Alessandri C., Breiteneder H., Ferreira F., Ciardiello M.A., Mari A.
    Allergy 66:870-877(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-118 AND 129-150, MASS SPECTROMETRY, ACETYLATION AT MET-1, ALLERGENICITY.
    Tissue: Fruit1 Publication.
  3. "Kirola, a new allergenic protein in kiwi fruit."
    D'Avino R., Camardella L., Ciardiello M.A., Tamburrini M., Carratore V.
    Submitted (APR-2008) to UniProtKB
    Cited for: MASS SPECTROMETRY.
    Tissue: Fruit1 Publication.

Entry informationi

Entry nameiKIRO_ACTDE
AccessioniPrimary (citable) accession number: P85524
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 11, 2016
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.