P85440 (ADH1_CATRO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Alcohol dehydrogenase 1 EC=1.1.1.1
Organism	Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
Taxonomic identifier	4058 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Gentianales › Apocynaceae › Rauvolfioideae › Vinceae › Catharanthus

Protein attributes

Sequence length	31 AA.
Sequence status	Fragments.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	An alcohol + NAD+ = an aldehyde or ketone + NADH.
Cofactor	Binds 2 zinc ions per subunit By similarity.
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family. Class-P subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding NAD Zinc
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	alcohol dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›31	›31	Alcohol dehydrogenase 1		PRO_0000324677
Sites
	Metal binding	7	1	Zinc 2 By similarity UniProtKB P00329
Experimental info
	Non-adjacent residues	11 – 12	2
	Non-terminal residue	1	1
	Non-terminal residue	31	1

Sequences

	Sequence		Length	Mass (Da)
	P85440 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 5EF8D543503B569D	FASTA	31	3,470
	10 20 30 SEESNLCDLL RDYDKPAQEV IAEMTDGGVD R

References

[1]	Varman P.A.M., Ranjitha Kumari B.D. Submitted (JAN-2008) to UniProtKB Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00059. ADH_ZINC. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADH1_CATRO

Accession

Primary (citable) accession number: P85440

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	March 18, 2008
Last modified:	June 28, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program