Reviewed, UniProtKB/Swiss-Prot P85440 (ADH1_CATRO)

Names and origin

Protein names	Recommended name:     Alcohol dehydrogenase 1     EC=1.1.1.1
Organism	Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
Taxonomic identifier	4058 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Gentianales › Apocynaceae › Rauvolfioideae › Vinceae › Catharanthus

Protein attributes

Sequence length	31 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	An alcohol + NAD(+) = an aldehyde or ketone + NADH.
Cofactor	Binds 2 zinc ions per subunit By similarity.
Subunit structure	Homodimer By similarity.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family. Class-P subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding NAD Zinc
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alcohol dehydrogenase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›31	›31	Alcohol dehydrogenase 1		PRO_0000324677
Sites
	Metal binding	7	1	Zinc 2 By similarity
Experimental info
	Non-adjacent residues	11 – 12	2
	Non-terminal residue	1	1
	Non-terminal residue	31	1

Sequences

	Sequence		Length	Mass (Da)
	P85440-1 [UniParc]. Last modified March 18, 2008. Version 1. Checksum: 5EF8D543503B569D	FASTA	31	3,470
	10 20 30 SEESNLCDLL RDYDKPAQEV IAEMTDGGVD R

References

[1]	Varman P.A.M., Ranjitha Kumari B.D. Submitted (JAN-2008) to UniProtKB Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR002328. AlcDHase_Zn_CS. [Graphical view]
PROSITE	PS00059. ADH_ZINC. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADH1_CATRO

Accession

Primary (citable) accession number: P85440

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	March 18, 2008
Last modified:	November 4, 2008
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)