Reviewed, UniProtKB/Swiss-Prot P85438 (ACAC_CATRO)

Names and origin

Protein names	Recommended name:     Acetyl-CoA carboxylase       Short name=ACC     EC=6.4.1.2
Organism	Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
Taxonomic identifier	4058 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Gentianales › Apocynaceae › Rauvolfioideae › Vinceae › Catharanthus

Protein attributes

Sequence length	31 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. UniProtKB Q00955
Pathway	Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. UniProtKB Q00955
Miscellaneous	On the 2D-gel the determined pI of this protein is: 4.86, its MW is: 16.9 kDa. Ref.1
Caution	The order of the peptides shown is unknown.
Mass spectrometry	Molecular mass is 16986 Da . Determined by MALDI. Ref.1

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetyl-CoA carboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›31	›31	Acetyl-CoA carboxylase		PRO_0000322590
Experimental info
	Non-adjacent residues	17 – 18	2
	Non-terminal residue	1	1
	Non-terminal residue	31	1

Sequences

	Sequence		Length	Mass (Da)
	P85438-1 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 8B6F4DD2307766FD	FASTA	31	3,398
	10 20 30 RISSSVIAHK TQLDSGKREV YSSHMQLGGP K

References

[1]	Varman P.A.M., Ranjitha Kumari B.D. Submitted (JAN-2008) to UniProtKB Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY.

Cross-references

3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	6.4.1.2. 20471.
Family and domain databases
PROSITE	PS50989. COA_CT_CTER. Partial match. PS50980. COA_CT_NTER. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACAC_CATRO

Accession

Primary (citable) accession number: P85438

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	February 26, 2008
Last modified:	October 13, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)