Reviewed, UniProtKB/Swiss-Prot P85347 (PER2_CYCRE)

Names and origin

Protein names	Recommended name:     Peroxidase 2     EC=1.11.1.7
Organism	Cycas revoluta (Sago palm)
Taxonomic identifier	3396 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Cycadophyta › Cycadales › Cycadaceae › Cycas

Protein attributes

Sequence length	15 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Catalytic activity	Donor + H2O2 = oxidized donor + 2 H2O. UniProtKB P22195
Cofactor	Binds 2 calcium ions per subunit By similarity. UniProtKB P22195 Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. UniProtKB P22195
Subcellular location	Secreted By similarity. UniProtKB P84516
Sequence similarities	Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Secreted
Ligand	Calcium Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›15	›15	Peroxidase 2		PRO_0000315884
Sites
	Metal binding	9	1	Iron (heme axial ligand) By similarity UniProtKB P22195
	Metal binding	10	1	Calcium 2 By similarity UniProtKB P22195
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	15	1

Sequences

	Sequence		Length	Mass (Da)
	P85347-1 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: D6D047F4379189B9	FASTA	15	1,509
	10 DLVALSGAHT IGQAR

References

[1]	Novo Uzal E., Gomez Ros L.V., Ros Barcelo A. Submitted (NOV-2007) to UniProtKB Cited for: PROTEIN SEQUENCE. Tissue: Callus.

Cross-references

3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.11.1.7. 264682.
Family and domain databases
InterPro	IPR019794. Peroxidases_AS. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view]
PROSITE	PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. Partial match. PS50873. PEROXIDASE_4. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PER2_CYCRE

Accession

Primary (citable) accession number: P85347

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	June 16, 2009
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)