P85290 (NDKB_MERBI) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 31, 2011.
Version 20.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Nucleoside diphosphate kinase B Short name=NDK B Short name=NDP kinase B EC=2.7.4.6 | ||
| Gene names |
| ||
| Organism | Merluccius bilinearis (Silver hake) | ||
| Taxonomic identifier | 79698 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Paracanthopterygii › Gadiformes › Merlucciidae › Merlucciinae › Merluccius |
Protein attributes
| Sequence length | 128 AA. |
| Sequence status | Fragments. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Major role in the synthesis of nucleoside triphosphates other than ATP By similarity. UniProtKB P15531 |
| Catalytic activity | ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. UniProtKB P15531 |
| Cofactor | Magnesium By similarity. UniProtKB P15531 |
| Subcellular location | Cytoplasm By similarity UniProtKB P15531. |
| Sequence similarities | Belongs to the NDK family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell cycle Nucleotide metabolism |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Magnesium Metal-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| PTM | Acetylation Phosphoprotein |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | CTP biosynthetic process Inferred from electronic annotation. Source: InterPro GTP biosynthetic processInferred from electronic annotation. Source: InterPro UTP biosynthetic processInferred from electronic annotation. Source: InterPro cell cycleInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW nucleoside diphosphate kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 128 | 128 | Nucleoside diphosphate kinase B | PRO_0000306186 | |||||
Sites | |||||||||
| Active site | 94 | 1 | Pros-phosphohistidine intermediate By similarity UniProtKB P15531 | ||||||
| Binding site | 9 | 1 | ATP By similarity UniProtKB P15531 | ||||||
| Binding site | 39 | 1 | ATP By similarity UniProtKB P15531 | ||||||
| Binding site | 70 | 1 | ATP By similarity UniProtKB P15531 | ||||||
| Binding site | 81 | 1 | ATP By similarity UniProtKB P15531 | ||||||
| Binding site | 91 | 1 | ATP By similarity UniProtKB P15531 | ||||||
Amino acid modifications | |||||||||
| Modified residue | 1 | 1 | N-acetylmethionine Ref.1 | ||||||
Experimental info | |||||||||
| Non-adjacent residues | 23 – 24 | 2 | |||||||
| Non-adjacent residues | 27 – 28 | 2 | |||||||
| Non-adjacent residues | 29 – 30 | 2 | |||||||
| Non-adjacent residues | 64 – 65 | 2 | |||||||
Sequences
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References
| [1] | "De novo mass spectrometry sequencing and characterization of species-specific peptides from nucleoside diphosphate kinase B for the classification of commercial fish species belonging to the family Merlucciidae." Carrera M., Canas B., Pineiro C., Vazquez J., Gallardo J.M. J. Proteome Res. 6:3070-3080(2007) [PubMed: 17622168] [Abstract] Cited for: PROTEIN SEQUENCE, ACETYLATION AT MET-1. Tissue: White muscle. |
Cross-references
3D structure databases | |
|---|---|
| ProteinModelPortal | P85290. |
| SMR | P85290. Positions 2-128. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Phylogenomic databases | |
| HOVERGEN | HBG000423. |
Family and domain databases | |
| InterPro | IPR001564. Nucleoside_diP_kinase. [Graphical view] |
| Gene3D | G3DSA:3.30.70.141. NDK. 2 hits. |
| PANTHER | PTHR11349. Nuc_diP_kinase_core. 1 hit. |
| Pfam | PF00334. NDK. 1 hit. [Graphical view] |
| SMART | SM00562. NDK. 1 hit. [Graphical view] |
| SUPFAM | SSF54919. NDK. 1 hit. |
| PROSITE | PS00469. NDP_KINASES. Partial match. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | NDKB_MERBI | ||||||||
| Accession | Primary (citable) accession number: P85290 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with