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Reviewed, UniProtKB/Swiss-Prot P85080 (GTF1_LEUME)

Last modified January 20, 2009. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Glucosyltransferase 1
    EC=2.4.1.5
Alternative name(s):
    Dextransucrase
    Sucrose 6-glucosyltransferase
    Glucansucrase
OrganismLeuconostoc mesenteroides
Taxonomic identifier1245 [NCBI]
Taxonomic lineageBacteriaFirmicutesLactobacillalesLeuconostoc

Protein attributes

Sequence length6 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris.

Catalytic activity

Sucrose + ((1->6)-alpha-D-glucosyl)(n) = D-fructose + ((1->6)-alpha-D-glucosyl)(n+1). Ref.1

Miscellaneous

Synthesizes water-soluble glucans (alpha 1,6-glucose). Ref.1

Sequence similarities

Belongs to the glycosyl hydrolase 70 family.

Biophysicochemical properties

Kinetic parameters:

KM=69.88 mM for sucrose Ref.1

pH dependence:

Optimum pH is 5.0. Ref.1

Temperature dependence:

Optimum temperature is 35 degrees Celsius. Ref.1

Ontologies

Keywords
   DiseaseDental caries
   Molecular functionGlycosyltransferase
Transferase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Molecular functiondextransucrase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›6›6Glucosyltransferase 1
PRO_0000284553

Experimental info

Non-terminal residue61

Sequences

Sequence LengthMass (Da)Tools
P85080-1 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: 72D1A451B5BAC000

FASTA6636
DSTNTV 

« Hide

References

[1]"Purification and characterization of glucansucrase from Leuconostoc mesentriodes AA1."
Aman A., Ul-qader S.A., Azhar A., Syed M.N.
Submitted (JAN-2007) to UniProtKB
Cited for: PROTEIN SEQUENCE, CATALYTIC ACTIVITY, BIOPHYSICOCHEMICAL PROPERTIES.
Strain: AA1.

Cross-references

3D structure databases

ModBaseSearch...

Enzyme and pathway databases

BRENDA2.4.1.5. 703.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameGTF1_LEUME
AccessionPrimary (citable) accession number: P85080
Entry history
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: January 20, 2009
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents