P85063 (ALLD3_ACTDE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Allergen Act d 3 Alternative name(s): Allergen Act d 3.01 Allergen Act d 3.02 Allergen=Act d 3
Organism	Actinidia deliciosa (Kiwi)
Taxonomic identifier	3627 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › Ericales › Actinidiaceae › Actinidia

Protein attributes

Sequence length	36 AA.
Sequence status	Fragments.
Protein existence	Evidence at protein level

General annotation (Comments)

Post-translational modification	N-glycosylated. Ref.1 Ref.2
Allergenic properties	Causes an allergic reaction in human. Binds IgE from 70% of kiwi-allergic patients. Ref.1 Ref.2
Mass spectrometry	Molecular mass is 40007±2 Da from positions 1 - ?. Determined by MALDI. Ref.1

Ontologies

Keywords
Disease	Allergen
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›36	›36	Allergen Act d 3		PRO_0000271418
Experimental info
	Non-adjacent residues	25 – 26	2
	Non-terminal residue	36	1

Sequences

	Sequence		Length	Mass (Da)
	P85063 [UniParc]. Last modified April 20, 2010. Version 3. Checksum: 5FF2D7B85AAD7FFC	FASTA	36	4,024
	10 20 30 FTDGLMKNGN FELAPKPEDM XGTVRVESLK AVKYXD

References

[1]

"Immunoglobulin E recognition patterns to purified Kiwifruit (Actinidinia deliciosa) allergens in patients sensitized to Kiwi with different clinical symptoms." Palacin A., Rodriguez J., Blanco C., Lopez-Torrejon G., Sanchez-Monge R., Varela J., Jimenez M.A., Cumplido J., Carrillo T., Crespo J.F., Salcedo G. Clin. Exp. Allergy 38:1220-1228(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-24, GLYCOSYLATION, MASS SPECTROMETRY, ALLERGEN. Strain: cv. Hayward. Tissue: Fruit.

[2]

"Purification and partial characterisation of a 40 kDa allergen from kiwifruit (Actinidia deliciosa) (Presentation at the XXV Congress of the European Academy of Allergology and Clinical Immunology, 10-14 June 2006, Vienna, Austria)." Bublin M., Radauer C., Lebens A., Knulst A., Scheiner O., Breiteneder H. Submitted (NOV-2006) to UniProtKB Cited for: PROTEIN SEQUENCE OF 1-15 AND 26-36, GLYCOSYLATION, ALLERGEN. Tissue: Fruit.

Cross-references

3D structure databases
ModBase	Search...
Protein family/group databases
Allergome	3553. Act d 3. 3556. Act d 3.0101.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ALLD3_ACTDE

Accession

Primary (citable) accession number: P85063
Secondary accession number(s): P84992

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	April 20, 2010
Last modified:	January 11, 2011
This is version 8 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program