Reviewed, UniProtKB/Swiss-Prot P85063 (ALLD3_ACTDE)

Names and origin

Protein names	Recommended name:     Allergen Act d 3 Alternative name(s):     Allergen=Act d 3
Organism	Actinidia deliciosa (Kiwi)
Taxonomic identifier	3627 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › Ericales › Actinidiaceae › Actinidia

Protein attributes

Sequence length	35 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Post-translational modification	N-glycosylated. Ref.2
Allergenic properties	Causes an allergic reaction in human. Binds IgE from 70% of kiwi-allergic patients. Ref.2 Ref.1
Mass spectrometry	Molecular mass is 40007±2 Da from positions 1 - ?. Determined by MALDI. Ref.1

Ontologies

Keywords
Disease	Allergen
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›35	›35	Allergen Act d 3		PRO_0000271418
Experimental info
	Sequence uncertainty	20	1	M or R Ref.1
	Non-adjacent residues	24 – 25	2
	Non-terminal residue	35	1

Sequences

	Sequence		Length	Mass (Da)
	P85063-1 [UniParc]. Last modified May 15, 2007. Version 2. Checksum: 924F8A3A54FC9F83	FASTA	35	3,913
	10 20 30 FTDGLMKNGN FELAPKPEDM GTVRVESLKA VKYXD

References

[1]

"IgE sensitization patterns to purified kiwifruit (Actinidinia deliciosa) allergens in patients allergic to kiwi with different clinical symptoms." Palacin A., Fernandez-Crespo J., Rodriguez J., Blanco C., Salcedo G. Submitted (SEP-2006) to UniProtKB Cited for: PROTEIN SEQUENCE OF 1-24, MASS SPECTROMETRY, ALLERGENICITY. Tissue: Fruit.

[2]

"Purification and partial characterisation of a 40 kDa allergen from kiwifruit (Actinidia deliciosa) (Presentation at the XXV Congress of the European Academy of Allergology and Clinical Immunology, 10-14 June 2006, Vienna, Austria)." Bublin M., Radauer C., Lebens A., Knulst A., Scheiner O., Breiteneder H. Submitted (NOV-2006) to UniProtKB Cited for: PROTEIN SEQUENCE OF 1-15 AND 25-35, GLYCOSYLATION, ALLERGENICITY. Tissue: Fruit.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ALLD3_ACTDE

Accession

Primary (citable) accession number: P85063
Secondary accession number(s): P84992

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	May 15, 2007
Last modified:	July 22, 2008
This is version 5 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)