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Protein

Bacteriocin divergicin M35

Gene
N/A
Organism
Carnobacterium divergens (Lactobacillus divergens)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Bacteriocin with antibacterial activity against many strains of L.monocytogenes, L.seeligeri, L.welshimeri, L.grayi, L.murayi, L.ivanovii, L.innocus, C.divergens and C.piscocola. No antibacterial activity was detected against L.lactis, P.acidilactici, P.pentosaceus, L.salivarius, L.delbruekii, L.acidophilus, L.plantarum, L.casei, L.rhamnosus, S.thermophilus, P.freudenreichii, B.breve and E.coli.1 Publication

Temperature dependencei

Displays a high degree of stability when incubated at temperatures of up to 121 degrees Celsius for 60 minutes.1 Publication

GO - Biological processi

  • cytolysis Source: UniProtKB-KW
  • defense response to Gram-positive bacterium Source: UniProtKB

Keywordsi

Molecular functionAntibiotic, Antimicrobial, Bacteriocin

Protein family/group databases

TCDBi1.C.24.1.13 the pediocin (pediocin) family

Names & Taxonomyi

Protein namesi
Recommended name:
Bacteriocin divergicin M35
OrganismiCarnobacterium divergens (Lactobacillus divergens)
Taxonomic identifieri2748 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesCarnobacteriaceaeCarnobacterium

Subcellular locationi

GO - Cellular componenti

  • extracellular region Source: UniProtKB

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Biotechnological usei

Has potential for use as a biopreservative for inhibiting L.monocytogenes in seafood products that do not usually undergo an adequate heat treatment.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00002506061 – 43Bacteriocin divergicin M35Add BLAST43

Proteomic databases

PRIDEiP84962

Structurei

3D structure databases

ProteinModelPortaliP84962
SMRiP84962
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacteriocin class IIA/YGNGV family.Sequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR002633 Bacteriocin_IIa
IPR023384 Bacteriocin_IIa_CS
PfamiView protein in Pfam
PF01721 Bacteriocin_II, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD004452 Bacteriocin_II, 1 hit
PROSITEiView protein in PROSITE
PS60030 BACTERIOCIN_IIA, 1 hit

Sequencei

Sequence statusi: Complete.

P84962-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
TKYYGNGVYC NSKKCWVDWG TAQGCIDVVI GQLGGGIPGK GKC
Length:43
Mass (Da):4,525
Last modified:October 3, 2006 - v1
Checksum:i3370AC1734B4DF55
GO

Mass spectrometryi

Molecular mass is 4518.75 Da from positions 1 - 43. Determined by MALDI. 1 Publication

Similar proteinsi

Entry informationi

Entry nameiDIV35_CARDV
AccessioniPrimary (citable) accession number: P84962
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 3, 2006
Last modified: May 23, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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