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Protein

Bacteriocin curvaticin

Gene
N/A
Organism
Lactobacillus curvatus
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Has antibacterial activity against the Gram-positive bacterium L.monocytogenes.1 Publication

pH dependencei

Stable below pH 6.1 Publication

Temperature dependencei

Stable below 60 degrees Celsius. Activity decreases sharply at temperatures above 60 degrees Celsius.1 Publication

GO - Biological processi

  • cytolysis Source: UniProtKB-KW
  • defense response to Gram-positive bacterium Source: UniProtKB

Keywordsi

Molecular functionAntibiotic, Antimicrobial, Bacteriocin

Names & Taxonomyi

Protein namesi
Recommended name:
Bacteriocin curvaticin
OrganismiLactobacillus curvatus
Taxonomic identifieri28038 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Subcellular locationi

GO - Cellular componenti

  • extracellular region Source: UniProtKB

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00002477271 – ›30Bacteriocin curvaticin1 PublicationAdd BLAST›30

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi9 ↔ 14By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP84886
SMRiP84886
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacteriocin class IIA/YGNGV family.Sequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR002633 Bacteriocin_IIa
PfamiView protein in Pfam
PF01721 Bacteriocin_II, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD004452 Bacteriocin_II, 1 hit

Sequencei

Sequence statusi: Fragment.

P84886-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30
AYPGNGVHCG KYSCTVDKQT AIGNIGNNAA
Length:30
Mass (Da):3,024
Last modified:July 25, 2006 - v1
Checksum:i30B0F30AC2BB062F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence uncertaintyi9C or K1 Publication1
Sequence uncertaintyi141 Publication1
Non-terminal residuei301 Publication1

Mass spectrometryi

Molecular mass is 4437 Da from positions 1 - ?. Determined by MALDI. 1 Publication

Entry informationi

Entry nameiCURVA_LACCU
AccessioniPrimary (citable) accession number: P84886
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 25, 2006
Last modified: February 28, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing