Reviewed, UniProtKB/Swiss-Prot P84820 (PORC_THELI)

Names and origin

Protein names

Recommended name:
    Pyruvate/ketoisovalerate oxidoreductases common subunit gamma
Including the following 2 domains:
    1- Recommended name:
            Pyruvate synthase subunit porC
              EC=1.2.7.1
        Alternative name(s):
            Pyruvate oxidoreductase gamma chain
              Short name=POR
            Pyruvic-ferredoxin oxidoreductase subunit gamma
    2- Recommended name:
            Ketoisovalerate oxidoreductase subunit vorC
                Short name=VOR
              EC=1.2.7.7
        Alternative name(s):
            2-oxoisovalerate oxidoreductase gamma chain
            2-oxoisovalerate ferredoxin reductase subunit gamma

Gene names

Name:

porG

Organism

Thermococcus litoralis

Taxonomic identifier

2265 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	15 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+). 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO(2) + 2 reduced ferredoxin + H(+).
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity Inferred from electronic annotation. Source: EC pyruvate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›15	›15	Pyruvate/ketoisovalerate oxidoreductases common subunit gamma		PRO_0000233958
Experimental info
	Non-terminal residue	15	1

Sequences

	Sequence		Length	Mass (Da)
	P84820-1 [UniParc]. Last modified May 2, 2006. Version 1. Checksum: 32F341A6A0331631	FASTA	15	1,628
	10 MIEIRFHGRG GQGAV

References

[1]

"Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A-dependent enzyme involved in peptide fermentation by hyperthermophilic archaea." Heider J., Mai X., Adams M.W.W. J. Bacteriol. 178:780-787(1996) [PubMed: 8550513] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: DSM 5473.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

PORC_THELI

Accession

Primary (citable) accession number: P84820
Secondary accession number(s): Q9UWG1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2006
Last sequence update:	May 2, 2006
Last modified:	November 4, 2008
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)