P84820 (PORC_THELI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pyruvate/ketoisovalerate oxidoreductases common subunit gamma

Including the following 2 domains:

1. Pyruvate synthase subunit porC
   EC=1.2.7.1
   Alternative name(s):
   Pyruvate oxidoreductase gamma chain
   Short name=POR
   Pyruvic-ferredoxin oxidoreductase subunit gamma
2. Ketoisovalerate oxidoreductase subunit vorC
   Short name=VOR
   EC=1.2.7.7
   Alternative name(s):
   2-oxoisovalerate ferredoxin reductase subunit gamma
   2-oxoisovalerate oxidoreductase gamma chain

Gene names

Name:

porG

Organism

Thermococcus litoralis

Taxonomic identifier

2265 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	15 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+. 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+.
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain. UniProtKB Q51799

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity Inferred from electronic annotation. Source: EC pyruvate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›15	›15	Pyruvate/ketoisovalerate oxidoreductases common subunit gamma UniProtKB Q51799		PRO_0000233958
Experimental info
	Non-terminal residue	15	1

Sequences

	Sequence		Length	Mass (Da)
	P84820 [UniParc]. Last modified May 2, 2006. Version 1. Checksum: 32F341A6A0331631	FASTA	15	1,628
	10 MIEIRFHGRG GQGAV

References

[1]

"Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A-dependent enzyme involved in peptide fermentation by hyperthermophilic archaea." Heider J., Mai X., Adams M.W.W. J. Bacteriol. 178:780-787(1996) [PubMed: 8550513] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: DSM 5473.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR019752. Pyrv/ketoisovalerate_OxRed_cat. [Graphical view]
Gene3D	G3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PORC_THELI

Accession

Primary (citable) accession number: P84820
Secondary accession number(s): Q9UWG1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2006
Last sequence update:	May 2, 2006
Last modified:	June 28, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program