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P84799 (PSMA_HALDO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proteasome subunit alpha

EC=3.4.25.1
Alternative name(s):
Multicatalytic endopeptidase complex subunit alpha
OrganismHalococcus dombrowskii
Taxonomic identifier179637 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalococcus

Protein attributes

Sequence length12 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH By similarity. UniProtKB Q60177

Catalytic activity

Cleavage of peptide bonds with very broad specificity.

Subunit structure

Composed of two subunits, alpha and beta. The complex is formed of four rings. The two outer rings are each composed of seven alpha subunits. The two inner rings are each composed of seven beta subunits By similarity. UniProtKB Q9V2V5

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the peptidase T1A family.

Ontologies

Keywords
   Cellular componentCytoplasm
Proteasome
   Molecular functionHydrolase
Protease
Threonine protease
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

proteasome complex

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionthreonine-type endopeptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›12›12Proteasome subunit alpha
PRO_0000228814

Experimental info

Non-terminal residue11
Non-terminal residue121

Sequences

Sequence LengthMass (Da)Tools
P84799 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 0B64E1E4D602C870

FASTA121,306
        10 
YGEPIGVETL TK 

« Hide

References

[1]Legat A., Stan-Lotter H.
Submitted (FEB-2006) to UniProtKB
Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry namePSMA_HALDO
AccessionPrimary (citable) accession number: P84799
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: March 21, 2006
Last modified: May 14, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries