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Protein

Trypsin inhibitor 3

Gene
N/A
Organism
Spinacia oleracea (Spinach)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Trypsin inhibitor.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei32 – 33Reactive bond for trypsinBy similarity2

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI90.002.

Names & Taxonomyi

Protein namesi
Recommended name:
Trypsin inhibitor 3
Alternative name(s):
SOTI III
Trypsin inhibitor III
OrganismiSpinacia oleracea (Spinach)
Taxonomic identifieri3562 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesChenopodiaceaeChenopodioideaeAnserineaeSpinacia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00002929391 – 37Trypsin inhibitor 3Add BLAST37

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi4 ↔ 21By similarity
Disulfide bondi11 ↔ 25By similarity
Disulfide bondi20 ↔ 36By similarity

Keywords - PTMi

Disulfide bond

Structurei

Secondary structure

137
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi9 – 11Combined sources3
Helixi17 – 19Combined sources3
Beta strandi25 – 27Combined sources3
Beta strandi29 – 36Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4AOQX-ray2.00D/E/F1-37[»]
4AORX-ray1.70D/E/F1-37[»]
SMRiP84781.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.By similarity

Sequence similaritiesi

Belongs to the Mirabilis serine proteinase inhibitor family.1 Publication

Keywords - Domaini

Knottin

Sequencei

Sequence statusi: Complete.

P84781-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
EDKCSPSGAI CSGFGPPEQC CSGACVPHPI LRIFVCQ
Length:37
Mass (Da):3,837
Last modified:June 26, 2007 - v1
Checksum:iD1F1F78D4EF22274
GO

Mass spectrometryi

Molecular mass is 3838.4 Da from positions 1 - 37. Determined by ESI. 1 Publication

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4AOQX-ray2.00D/E/F1-37[»]
4AORX-ray1.70D/E/F1-37[»]
SMRiP84781.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiI90.002.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiITR3_SPIOL
AccessioniPrimary (citable) accession number: P84781
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 26, 2007
Last modified: November 2, 2016
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.