Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P84781

- ITR3_SPIOL

UniProt

P84781 - ITR3_SPIOL

Protein

Trypsin inhibitor 3

Gene
N/A
Organism
Spinacia oleracea (Spinach)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Trypsin inhibitor.1 Publication

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei32 – 332Reactive bond for trypsinBy similarity

    GO - Molecular functioni

    1. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Protease inhibitor, Serine protease inhibitor

    Protein family/group databases

    MEROPSiI90.002.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Trypsin inhibitor 3
    Alternative name(s):
    SOTI III
    Trypsin inhibitor III
    OrganismiSpinacia oleracea (Spinach)
    Taxonomic identifieri3562 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesAmaranthaceaeChenopodioideaeAnserineaeSpinacia

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Peptidei1 – 3737Trypsin inhibitor 3PRO_0000292939Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi4 ↔ 21By similarity
    Disulfide bondi11 ↔ 25By similarity
    Disulfide bondi20 ↔ 36By similarity

    Keywords - PTMi

    Disulfide bond

    Structurei

    Secondary structure

    1
    37
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi9 – 113
    Helixi17 – 193
    Beta strandi25 – 273
    Beta strandi29 – 368

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4AOQX-ray2.00D/E/F1-37[»]
    4AORX-ray1.70D/E/F1-37[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domaini

    The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.By similarity

    Sequence similaritiesi

    Belongs to the Mirabilis serine proteinase inhibitor family.1 Publication

    Keywords - Domaini

    Knottin

    Sequencei

    Sequence statusi: Complete.

    P84781-1 [UniParc]FASTAAdd to Basket

    « Hide

    EDKCSPSGAI CSGFGPPEQC CSGACVPHPI LRIFVCQ                 37
    Length:37
    Mass (Da):3,837
    Last modified:June 26, 2007 - v1
    Checksum:iD1F1F78D4EF22274
    GO

    Mass spectrometryi

    Molecular mass is 3838.4 Da from positions 1 - 37. Determined by ESI. 1 Publication

    Cross-referencesi

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4AOQ X-ray 2.00 D/E/F 1-37 [» ]
    4AOR X-ray 1.70 D/E/F 1-37 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi I90.002.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Trypsin inhibitors from the garden four o'clock (Mirabilis jalapa) and spinach (Spinacia oleracea) seeds: isolation, characterization and chemical synthesis."
      Kowalska J., Pszczola K., Wilimowska-Pelc A., Lorenc-Kubis I., Zuziak E., Lugowski M., Legowska A., Kwiatkowska A., Sleszynska M., Lesner A., Walewska A., Zablotna E., Rolka K., Wilusz T.
      Phytochemistry 68:1487-1496(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE, FUNCTION, MASS SPECTROMETRY.
      Tissue: Seed1 Publication.

    Entry informationi

    Entry nameiITR3_SPIOL
    AccessioniPrimary (citable) accession number: P84781
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 26, 2007
    Last sequence update: June 26, 2007
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3