Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ig heavy chain Mem5

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Anti-influenza H3N2 neuraminidase antibody.1 Publication

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain Mem5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000599011 – ›237Ig heavy chain Mem5Add BLAST›237

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi22 ↔ 98PROSITE-ProRule annotationBy similarity
Disulfide bondi135Interchain (with a light chain)PROSITE-ProRule annotationBy similarity
Disulfide bondi147 ↔ 202PROSITE-ProRule annotationBy similarity
Disulfide bondi227Interchain (with a heavy chain)PROSITE-ProRule annotationBy similarity
Disulfide bondi230Interchain (with a heavy chain)PROSITE-ProRule annotationBy similarity
Disulfide bondi232Interchain (with a heavy chain)PROSITE-ProRule annotationBy similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP84751.
PeptideAtlasiP84751.
PRIDEiP84751.

Structurei

Secondary structure

1237
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 8Combined sources6
Beta strandi10 – 12Combined sources3
Beta strandi18 – 27Combined sources10
Helixi29 – 31Combined sources3
Beta strandi33 – 39Combined sources7
Beta strandi45 – 51Combined sources7
Helixi54 – 56Combined sources3
Beta strandi60 – 62Combined sources3
Turni64 – 66Combined sources3
Helixi67 – 69Combined sources3
Beta strandi70 – 75Combined sources6
Helixi76 – 78Combined sources3
Beta strandi80 – 85Combined sources6
Helixi90 – 92Combined sources3
Beta strandi94 – 102Combined sources9
Turni103 – 105Combined sources3
Beta strandi106 – 110Combined sources5
Beta strandi114 – 118Combined sources5
Beta strandi127 – 131Combined sources5
Helixi135 – 138Combined sources4
Beta strandi139 – 155Combined sources17
Beta strandi158 – 161Combined sources4
Helixi162 – 164Combined sources3
Beta strandi170 – 172Combined sources3
Beta strandi176 – 178Combined sources3
Beta strandi181 – 191Combined sources11
Turni192 – 197Combined sources6
Beta strandi201 – 206Combined sources6
Helixi207 – 209Combined sources3
Beta strandi211 – 216Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ZANX-ray1.70H2-220[»]
2ADFX-ray1.90H108-220[»]
2AEPX-ray2.10H1-217[»]
2AEQX-ray3.00H1-217[»]
2G2RX-ray2.75B/H109-221[»]
2G5BX-ray2.30F1-219[»]
3BKCX-ray1.90H92-227[»]
3BKJX-ray1.59H92-220[»]
3BKMX-ray1.60H92-220[»]
4HDIX-ray2.45B/H2-220[»]
ProteinModelPortaliP84751.
SMRiP84751.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP84751.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 119Ig-like 1Sequence analysisAdd BLAST119
Domaini126 – 218Ig-like 2Sequence analysisAdd BLAST93

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni101 – 105D segmentBy similarity5
Regioni106 – 120JH2 segment1 PublicationAdd BLAST15

Sequence similaritiesi

Contains 2 Ig-like (immunoglobulin-like) domains.Sequence analysis

Keywords - Domaini

Immunoglobulin C region, Immunoglobulin domain, Immunoglobulin V region, Repeat

Phylogenomic databases

HOVERGENiHBG005814.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P84751-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EVKLVESGGG LVQPGGSLSL SCATSGFTFI DYYMSWFRQP PGKALEWLGL
60 70 80 90 100
IRNKGNGYTM EYSASLKGRF TISRDNSQSI VYLHMNTLTA EDSATYYCAR
110 120 130 140 150
VDYGTNYDYW GQGTTLTVSS AKTTAPSVYP LAPVCGDTTG SSVTLGCLVK
160 170 180 190 200
GYFPEPVTLT WNSGSLSSGV HTFPAVLQSD LYTLSSSVTV TSSTWPSQSI
210 220 230
TCNVAHPASS TKVDKKIEPR GPTIKPCPPC KCPAPNS
Length:237
Mass (Da):25,350
Last modified:January 24, 2006 - v1
Checksum:i6BFABA1E6F835C10
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei237Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ220746 mRNA. Translation: ABB81885.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ220746 mRNA. Translation: ABB81885.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ZANX-ray1.70H2-220[»]
2ADFX-ray1.90H108-220[»]
2AEPX-ray2.10H1-217[»]
2AEQX-ray3.00H1-217[»]
2G2RX-ray2.75B/H109-221[»]
2G5BX-ray2.30F1-219[»]
3BKCX-ray1.90H92-227[»]
3BKJX-ray1.59H92-220[»]
3BKMX-ray1.60H92-220[»]
4HDIX-ray2.45B/H2-220[»]
ProteinModelPortaliP84751.
SMRiP84751.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

IMGTiSearch...

Proteomic databases

MaxQBiP84751.
PeptideAtlasiP84751.
PRIDEiP84751.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG005814.

Miscellaneous databases

EvolutionaryTraceiP84751.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHVM63_MOUSE
AccessioniPrimary (citable) accession number: P84751
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: January 24, 2006
Last modified: November 2, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.