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Protein

Photoactivated adenylate cyclase subunit beta-like protein FB

Gene

pacB

Organism
Euglena gracilis
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

The FB strain is deficient in phototaxis. It is not known if this is due to defective adenylate cyclase activity or defective BLUF domains in this protein. In wild-type E.gracilis, photoactivated adenylate cyclase is found in the paraxonemal bodies (PABs). PABs are not visible in all cells in this strain, and are smaller than in wild-type.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Photoactivated adenylate cyclase subunit beta-like protein FB
Gene namesi
Name:pacBImported
OrganismiEuglena gracilis
Taxonomic identifieri3039 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaEuglenidaEuglenalesEuglenaceaeEuglena

Subcellular locationi

  • flagellum 1 Publication
  • Note: Paraxonemal body. And paraxonemal bodies (PABs).

GO - Cellular componenti

  • intracellular Source: GOC
  • motile cilium Source: UniProtKB

Keywords - Cellular componenti

Cell projection, Cilium, Flagellum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001957241 – 859Photoactivated adenylate cyclase subunit beta-like protein FBAdd BLAST859

Interactioni

Subunit structurei

Heterotetramer of two alpha and two beta subunits.By similarity

Structurei

3D structure databases

ProteinModelPortaliP84741
SMRiP84741
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 149BLUF 1PROSITE-ProRule annotationAdd BLAST94
Domaini205 – 333Guanylate cyclase 1PROSITE-ProRule annotationAdd BLAST129
Domaini471 – 563BLUF 2PROSITE-ProRule annotationAdd BLAST93
Domaini619 – 748Guanylate cyclase 2PROSITE-ProRule annotationAdd BLAST130

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di3.30.70.1230, 2 hits
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR036046 Acylphosphatase-like_dom_sf
IPR007024 BLUF_domain
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF04940 BLUF, 2 hits
PF00211 Guanylate_cyc, 2 hits
SMARTiView protein in SMART
SM01034 BLUF, 2 hits
SUPFAMiSSF54975 SSF54975, 2 hits
SSF55073 SSF55073, 2 hits
PROSITEiView protein in PROSITE
PS50925 BLUF, 2 hits
PS50125 GUANYLATE_CYCLASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

P84741-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYILVWKKGQ QIKTFHTLDE AAQFKAASNI DEAQMFSVTV APAISASGGS
60 70 80 90 100
NEATNLRRLM YLSKSTNPEE CNPQFLAEMA RVATIRNREI GVSGFLMYSS
110 120 130 140 150
PFSFQVIEGT DEDLDFLFAK ISADPRHERC IVLANGPCTG RMYGDWHMKD
160 170 180 190 200
SHMDSITTHP AMKTILYQIA RSFSSMWSYL PKSAGNMLLL GKDPAAQPPE
210 220 230 240 250
PMSVVVTFIY LVEFGSILSN PNLTDQAAEV LSTFVDVCVK NVEGSGGNIA
260 270 280 290 300
KFITGICMAY WPINRTEEAL TAIQQISEDL AQLRSQQAPG SAVSLMYSQA
310 320 330 340 350
GVHYGRPMLC NAGRRKSDFT LLGDCINTTS RIATLAKKFK TPLLFSQEVR
360 370 380 390 400
CLLRDEMREE IVGAGMHQVK GRDKPVVVYQ FPGPELDVEM VRQKIEQFTP
410 420 430 440 450
GRFRCQMPVV EYEGLPNSQR PPIFDDTPKA NRRPRTPGYG GRQRSDSQVD
460 470 480 490 500
RPIMIAKLAG PSVSATGDTT LTTLTYISQA TRPMSRQDLS AIMRTATRRN
510 520 530 540 550
AQQSITGTLL HVNGLFVQTL EGPKDAVANL YLRVRQDPRQ TDVTTVHMAP
560 570 580 590 600
LQERVYPSEW TLTSATAEML ATFPPLQDVL AQLAKSFTSL ETYVPSTVVR
610 620 630 640 650
HLTAGNNPRN LMPVSCGVVM LATDICSFTS LTEKSSLTEV WMICNTFIDA
660 670 680 690 700
CTSAICQDGR EVIKLIGDCV TAYSPGNNAD SAVAAAQELF TFCRQLREAF
710 720 730 740 750
VDVLDVRGCV SCGVGLEYGQ VVMAQCGSMG LTEYVVAGAV SARVMEVEAI
760 770 780 790 800
TREVGYAIVV TEPVADRLSP QLRDHGIVPT PQAIEGLPCY GIAGEEFELD
810 820 830 840 850
VDSIKRGIKA LHAARSGEKP LTEPEAAKPD FRVSPGRVRH GDSGRRSNSA

QGKRSIQVR
Length:859
Mass (Da):94,248
Last modified:January 10, 2006 - v1
Checksum:iF7C4D688610C8EF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181339 mRNA Translation: CAJ57398.1

Similar proteinsi

Entry informationi

Entry nameiPBLFB_EUGGR
AccessioniPrimary (citable) accession number: P84741
Secondary accession number(s): Q2P9M6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: October 25, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health