P84711 (BAP3_LACCU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Bioactive peptide 3 Short name=BAP3
Organism	Lactobacillus curvatus
Taxonomic identifier	28038 [NCBI]
Taxonomic lineage	Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	9 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Has antibacterial activity against the Gram-positive bacteria L.monocytogenes, L.lactis subsp lactis and L.curvatus H28, but not against the Gram-positive bacteria L.curvatus CWBI-B28, L.brevis and L.plantarum or the Gram-negative bacteria E.coli and Pseudomonas sp 55. Has no antifungal activity against S.cerevisiae, Penicillium sp BKS-TAN2 or A.niger. Ref.1
Subcellular location	Secreted › extracellular space Ref.1.
Post-translational modification	Contains one disulfide bond. Ref.1

Ontologies

Keywords
Cellular component	Secreted
Molecular function	Antibiotic Antimicrobial Bacteriocin
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	cytolysis Inferred from electronic annotation. Source: UniProtKB-KW defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular space Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Peptide	1 – ›9	›9	Bioactive peptide 3 Ref.1		PRO_0000223897
Experimental info
	Non-terminal residue	9	1

Sequences

	Sequence		Length	Mass (Da)
	P84711 [UniParc]. Last modified February 21, 2006. Version 1. Checksum: 0687B771A736C760	FASTA	9	980
	NIPQLTPTP

References

[1]	"Production of three anti-listerial peptides by Lactobacillus curvatus in MRS broth." Ghalfi H., Benkerroum N., Ongena M., Bensaid M., Thonart P. Food Res. Intern. 43:33-39(2010) Cited for: PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, DISULFIDE BOND. Strain: CWBI-B28.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

BAP3_LACCU

Accession

Primary (citable) accession number: P84711

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2006
Last sequence update:	February 21, 2006
Last modified:	August 10, 2010
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program