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P84546

- ACCC_POPEU

UniProt

P84546 - ACCC_POPEU

Protein

Biotin carboxylase

Gene
N/A
Organism
Populus euphratica (Euphrates poplar)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.By similarity

    Catalytic activityi

    ATP + biotin-[carboxyl-carrier-protein] + CO2 = ADP + phosphate + carboxy-biotin-[carboxyl-carrier-protein].
    ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.

    Pathwayi

    GO - Molecular functioni

    1. acetyl-CoA carboxylase activity Source: UniProtKB-EC
    2. ATP binding Source: UniProtKB-KW
    3. biotin carboxylase activity Source: UniProtKB-EC

    GO - Biological processi

    1. fatty acid biosynthetic process Source: UniProtKB-KW
    2. malonyl-CoA biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

    Keywords - Ligandi

    ATP-binding, Biotin, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00655; UER00711.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Biotin carboxylase (EC:6.3.4.14)
    Alternative name(s):
    Acetyl-CoA carboxylase subunit A (EC:6.4.1.2)
    Short name:
    ACC
    OrganismiPopulus euphratica (Euphrates poplar)
    Taxonomic identifieri75702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesSalicaceaeSaliceaePopulus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – ›40›40Biotin carboxylasePRO_0000146795Add
    BLAST

    Proteomic databases

    PRIDEiP84546.

    Interactioni

    Subunit structurei

    Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.By similarity

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini‹1 – ›40›40Biotin carboxylationSequence AnalysisAdd
    BLAST
    Domaini‹13 – ›27›15ATP-graspPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 ATP-grasp domain.By similarityPROSITE-ProRule annotation
    Contains 1 biotin carboxylation domain.By similarity

    Sequencei

    Sequence statusi: Fragments.

    P84546-1 [UniParc]FASTAAdd to Basket

    « Hide

    ILVANRGEIA VRLLEEAPSP ALTPELRITA YLPSGGPFVR              40
    Length:40
    Mass (Da):4,288
    Last modified:June 21, 2005 - v1
    Checksum:i1D3B610C28C4E4D1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11
    Non-adjacent residuesi12 – 132Curated
    Non-adjacent residuesi27 – 282Curated
    Non-terminal residuei40 – 401

    Cross-referencesi

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P84546.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00655 ; UER00711 .

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Proteome profiling of Populus euphratica Oliv. upon heat stress."
      Ferreira S., Hjernoe K., Larsen M., Wingsle G., Larsen P., Fey S., Roepstorff P., Pais M.S.
      Ann. Bot. 98:361-377(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Tissue: Leaf.

    Entry informationi

    Entry nameiACCC_POPEU
    AccessioniPrimary (citable) accession number: P84546
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 21, 2005
    Last sequence update: June 21, 2005
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3