Reviewed, UniProtKB/Swiss-Prot P84538 (CYSK_POPEU)

Names and origin

Protein names	Recommended name:     Cysteine synthase       Short name=CSase     EC=2.5.1.47 Alternative name(s):     O-acetylserine sulfhydrylase     O-acetylserine (thiol)-lyase       Short name=OAS-TL
Organism	Populus euphratica (Euphrates poplar)
Taxonomic identifier	75702 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids I › Malpighiales › Salicaceae › Saliceae › Populus

Protein attributes

Sequence length	29 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. UniProtKB Q00834
Cofactor	Pyridoxal phosphate By similarity. UniProtKB Q00834
Pathway	Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.
Subunit structure	Homodimer By similarity. UniProtKB Q00834
Subcellular location	Cytoplasm By similarity. UniProtKB Q00834
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis
Cellular component	Cytoplasm
Ligand	Pyridoxal phosphate
Molecular function	Transferase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	cysteine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›29	›29	Cysteine synthase		PRO_0000167123
Experimental info
	Non-adjacent residues	17 – 18	2
	Non-terminal residue	1	1
	Non-terminal residue	29	1

Sequences

	Sequence		Length	Mass (Da)
	P84538-1 [UniParc]. Last modified June 21, 2005. Version 1. Checksum: F131D660D6AA8E05	FASTA	29	3,292
	10 20 TPNSYILQQF ENPANPKLIV AIFPSFGER

References

[1]	"Proteome profiling of Populus euphratica Oliv. upon heat stress." Ferreira S., Hjernoe K., Larsen M., Wingsle G., Larsen P., Fey S., Roepstorff P., Pais M.S. Ann. Bot. 98:361-377(2006) [PubMed: 16740589] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Leaf.

Cross-references

3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.5.1.47. 293088.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. [Graphical view]
PROSITE	PS00901. CYS_SYNTHASE. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYSK_POPEU

Accession

Primary (citable) accession number: P84538

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 21, 2005
Last sequence update:	June 21, 2005
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)