Reviewed, UniProtKB/Swiss-Prot P84468 (FERA_PARDE)

Names and origin

Protein names

Recommended name:
    Ferric reductase A
    EC=1.16.1.7

Gene names

Name:

ferA

Organism

Paracoccus denitrificans

Taxonomic identifier

266 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length	20 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Reductase activity that acts on Fe3+-chelates and NADH as an electron donor and requires the presence of FMN for full activity. May play a role in iron uptake. Ref.1
Catalytic activity	2 Fe2+ + NAD+ = 2 Fe3+ + NADH. Ref.1
Subunit structure	Monomer. Ref.1
Induction	By Fe3+ ion deprivation. Ref.1
Mass spectrometry	Molecular mass is 18814 Da from positions 1 - ?. Determined by MALDI. It is not clear why there are 2 peaks for this protein. Ref.1 Molecular mass is 18917 Da from positions 1 - ?. Determined by MALDI. Ref.1

Ontologies

Keywords
Biological process	Electron transport Transport
Ligand	FMN Flavoprotein NAD
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ferric-chelate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›20	›20	Ferric reductase A		PRO_0000087227
Experimental info
	Non-terminal residue	20	1

Sequences

	Sequence		Length	Mass (Da)
	P84468-1 [UniParc]. Last modified March 29, 2005. Version 1. Checksum: F9884FCE24EA0F5A	FASTA	20	2,246
	10 20 SRLPPATRDK LADEITFFPA

References

[1]

"Isolation and biochemical characterization of two soluble iron(III) reductases from Paracoccus denitrificans." Mazoch J., Tesarik R., Sedlacek V., Kucera I., Turanek J. Eur. J. Biochem. 271:553-562(2004) [PubMed: 14728682] [Abstract] Cited for: PROTEIN SEQUENCE, FUNCTION, CATALYTIC ACTIVITY, SUBUNIT, INDUCTION, MASS SPECTROMETRY.

Cross-references

3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.16.1.7. 59.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

FERA_PARDE

Accession

Primary (citable) accession number: P84468

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2005
Last sequence update:	March 29, 2005
Last modified:	January 20, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)