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Protein

Bombesin

Gene
N/A
Organism
Bombina bombina (Fire-bellied toad)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Stimulates smooth muscle contraction. Role in induction of hypothermia, stimulation of DNA replication and release of many gastrointestinal hormones (By similarity).By similarity

GO - Biological processi

Keywordsi

Molecular functionAmphibian defense peptide

Names & Taxonomyi

Protein namesi
Recommended name:
Bombesin
OrganismiBombina bombina (Fire-bellied toad)
Taxonomic identifieri8345 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraBombinatoridaeBombina

Subcellular locationi

  • Secreted 1 Publication

GO - Cellular componenti

  • extracellular region Source: UniProtKB

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00000434881 – 14BombesinAdd BLAST14

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1Pyrrolidone carboxylic acidBy similarity1
Modified residuei14Methionine amideBy similarity1

Keywords - PTMi

Amidation, Pyrrolidone carboxylic acid

Expressioni

Tissue specificityi

Expressed by the skin glands.1 Publication

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR000874. Bombesin.
PfamiView protein in Pfam
PF02044. Bombesin. 1 hit.
PROSITEiView protein in PROSITE
PS00257. BOMBESIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Length:14
Mass (Da):1,638
Last modified:November 9, 2004 - v1
Checksum:iCF36E4D3BCDC9666
GO

Sequence databases

PIRiA01564. BSTD.

Similar proteinsi

Entry informationi

Entry nameiBOMB_BOMBO
AccessioniPrimary (citable) accession number: P84214
Secondary accession number(s): P01296
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: November 9, 2004
Last modified: October 1, 2014
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families