Reviewed, UniProtKB/Swiss-Prot P84209 (MDHM_IMPCY)

Names and origin

Protein names	Recommended name:     Malate dehydrogenase, mitochondrial     EC=1.1.1.37
Organism	Imperata cylindrica (Cogon grass)
Taxonomic identifier	80369 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › PACCAD clade › Panicoideae › Andropogoneae › Imperata

Protein attributes

Sequence length	31 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	(S)-malate + NAD+ = oxaloacetate + NADH. UniProtKB P61889
Subunit structure	Homodimer By similarity. UniProtKB P61889
Subcellular location	Mitochondrion matrix By similarity.
Sequence similarities	Belongs to the LDH/MDH superfamily. MDH type 1 family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Cellular component	Mitochondrion
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	malate metabolic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	L-malate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›31	›31	Malate dehydrogenase, mitochondrial		PRO_0000113339
Regions
	Nucleotide binding	9 – ›19	›11	NAD By similarity UniProtKB P61889
	Nucleotide binding	‹20 – ›31	›12	NAD By similarity UniProtKB P61889
Experimental info
	Non-adjacent residues	19 – 20	2
	Non-terminal residue	1	1
	Non-terminal residue	31	1

Sequences

	Sequence		Length	Mass (Da)
	P84209-1 [UniParc]. Last modified November 9, 2004. Version 1. Checksum: 9E5D7F740CA4461D	FASTA	31	3,110
	10 20 30 VAILGAAGGI GQPLSLLMKD DLFNINAGIV K

References

[1]	Chang I.-F., Kangling Z., Chou C.-H. Submitted (JUL-2004) to UniProtKB Cited for: PROTEIN SEQUENCE. Strain: cv. Major. Tissue: Leaf.

Cross-references

3D structure databases
ModBase	Search...
Organism-specific databases
Gramene	P84209.
Enzyme and pathway databases
BRENDA	1.1.1.37. 301243.
Family and domain databases
InterPro	IPR001236. Lactate/malate_DH. IPR001252. Malate_DH_AS. IPR010097. Malate_DH_NAD-dep_euk_g_bac. [Graphical view]
PANTHER	PTHR11540:SF1. MDH_euk_g_bac. 1 hit.
Pfam	PF00056. Ldh_1_N. 1 hit. [Graphical view]
PROSITE	PS00068. MDH. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MDHM_IMPCY

Accession

Primary (citable) accession number: P84209

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 9, 2004
Last sequence update:	November 9, 2004
Last modified:	June 16, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)