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P84196 (GUNB_GLOTR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase Cel12A

EC=3.2.1.4
Alternative name(s):
Cellulase
Endo-1,4-beta-glucanase
OrganismGloeophyllum trabeum (Brown rot fungus)
Taxonomic identifier104355 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesGloeophyllalesGloeophyllaceaeGloeophyllum

Protein attributes

Sequence length36 AA.
Sequence statusFragments.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Has carboxymethylcellulase activity. Ref.1

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. Ref.1

Subcellular location

Secretedextracellular space Ref.1.

Sequence similarities

Belongs to the glycosyl hydrolase 12 (cellulase H) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   Molecular functionGlycosidase
Hydrolase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from direct assay Ref.1. Source: UniProtKB

   Cellular_componentextracellular region

Inferred from direct assay Ref.1. Source: UniProtKB

extracellular space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncellulase activity

Inferred from direct assay Ref.1. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›36›36Endoglucanase Cel12A
PRO_0000184073

Experimental info

Non-adjacent residues13 – 142
Non-adjacent residues26 – 272
Non-terminal residue11
Non-terminal residue361

Sequences

Sequence LengthMass (Da)Tools
P84196 [UniParc].

Last modified July 19, 2005. Version 1.
Checksum: C3F54CFA98627D90

FASTA363,726
        10         20         30 
GVQISQISSF PTTADVSYDF NITNALGGIQ PVGSLK 

« Hide

References

[1]"Processive endoglucanase active in crystalline cellulose hydrolysis by the brown rot basidiomycete Gloeophyllum trabeum."
Cohen R., Suzuki M.R., Hammel K.E.
Appl. Environ. Microbiol. 71:2412-2417(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE, FUNCTION, CATALYTIC ACTIVITY, SUBCELLULAR LOCATION.
Strain: ATCC 11539.

Cross-references

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH12. Glycoside Hydrolase Family 12.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-16932.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameGUNB_GLOTR
AccessionPrimary (citable) accession number: P84196
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: February 19, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries