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Protein
Submitted name:

Chondroitinase (Chondroitin lyase)

Gene
N/A
Organism
Paenarthrobacter aurescens (Arthrobacter aurescens)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei242N-acetyl-D-glucosamineCombined sources1
Binding sitei296N-acetyl-D-glucosamineCombined sources1
Binding sitei300N-acetyl-D-glucosamineCombined sources1

GO - Molecular functioni

GO - Biological processi

Protein family/group databases

CAZyiPL8. Polysaccharide Lyase Family 8.

Names & Taxonomyi

Protein namesi
Submitted name:
Chondroitinase (Chondroitin lyase)Imported
OrganismiPaenarthrobacter aurescens (Arthrobacter aurescens)Imported
Taxonomic identifieri43663 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaePaenarthrobacter

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Chemistry databases

DrugBankiDB03284. 2,6-Anhydro-3-Deoxy-D-Erythro-Hex-2-Enonic Acid.
DB01872. 2-deoxy-2-acetamido-beta-D-galactose-4-sulfate.
DB02227. 4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RW9X-ray1.35A1-757[»]
1RWAX-ray1.30A1-757[»]
1RWCX-ray1.90A1-757[»]
1RWFX-ray1.45A1-757[»]
1RWGX-ray1.50A1-757[»]
1RWHX-ray1.25A1-757[»]
ProteinModelPortaliP84141.
SMRiP84141.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP84141.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 336Lyase_8_NInterPro annotationAdd BLAST321
Domaini376 – 633Lyase_8InterPro annotationAdd BLAST258
Domaini648 – 710Lyase_8_CInterPro annotationAdd BLAST63

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni124 – 126N-acetyl-D-glucosamine bindingCombined sources3

Family and domain databases

Gene3Di1.50.10.100. 1 hit.
2.60.220.10. 1 hit.
2.70.98.10. 1 hit.
InterProiView protein in InterPro
IPR008929. Chondroitin_lyas.
IPR011013. Gal_mutarotase_sf_dom.
IPR014718. GH-type_carb-bd.
IPR011071. Lyase_8-like_C.
IPR012970. Lyase_8_alpha_N.
IPR004103. Lyase_8_C.
IPR003159. Lyase_8_central_dom.
PfamiView protein in Pfam
PF02278. Lyase_8. 1 hit.
PF02884. Lyase_8_C. 1 hit.
PF08124. Lyase_8_N. 1 hit.
SUPFAMiSSF48230. SSF48230. 1 hit.
SSF49863. SSF49863. 1 hit.
SSF74650. SSF74650. 1 hit.

Sequencei

Sequence statusi: Complete.

P84141-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EAEPGAAEFA ALRNRWVDQI TGRNVIQAGD PDFAKAITAL NNKAADSLAK
60 70 80 90 100
LDVKKGRTSV FTDLSLAKDA EMVTTYTRLS QLATAWATPT AAVFGDAAVL
110 120 130 140 150
AAIKAGLADA NTLCYNDRKE EVGNWWSWEI GVPRALADAM VLLHAELSAA
160 170 180 190 200
ERTAYCAAID HFVPDPWLQF PPKRGKITSV GANRVDLCQG IIIRSLAGED
210 220 230 240 250
PTKLNHAVAG LSQVWQYVTS GDGIFRDGSF IQHSTTPYTG SYGVVLLTGL
260 270 280 290 300
SKLFSLLGGT AFEVSDPTRS IFFDAVEGSF APVMINGAMA DAVRGRSISR
310 320 330 340 350
EANTGYDLGA SAIEAILLLA RAMDPATAAR WRGLCAGWIA RDTYRPILNS
360 370 380 390 400
ASVPRTALVK QLEATGVAPV AEATGHKLFP AMDRTMHRGP GWALSLALSS
410 420 430 440 450
NRIAWYECGN GENNRGYHTG SGMTYFYTSD LGQYDDAFWA TANYNRLPGI
460 470 480 490 500
TVDTTPLPDK VEGQWGAAVP ADEWSGATAL GEVAAVGQHL VGPGRTGLTA
510 520 530 540 550
RKSWFVSGDV TVCLGADIST ASGAKVETIV DHRNLHQGSN TLTTAAGTIA
560 570 580 590 600
GTAGTVEVLG DGRWVHLEGF GGYAMLDDSP LHVLRETRSG SWSGVNINGS
610 620 630 640 650
ATVQQRNFAT LYVNHGVGPV AGSYAYMVAP GASVDLTRKL LEGNKYSVIR
660 670 680 690 700
NDATAQSVEF KTAKTTAATF WKPGMAGDLG ASGPACVVFS RHGNELSLAV
710 720 730 740 750
SEPTQKAAGL TLTLPEGTWS SVLEGAGTLG TDADGRSTLT LDTTGLSGKT

KLIKLKR
Length:757
Mass (Da):79,928
Last modified:September 13, 2004 - v1
Checksum:iA461E54AF0F3D88A
GO

Similar proteinsi

Entry informationi

Entry nameiP84141_PAEAU
AccessioniPrimary (citable) accession number: P84141
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: November 22, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources