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Protein

60S ribosomal protein L19

Gene

Rpl19

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • 5.8S rRNA binding Source: RGD
  • large ribosomal subunit rRNA binding Source: RGD
  • RNA binding Source: RGD
  • structural constituent of ribosome Source: RGD

GO - Biological processi

  • cytoplasmic translation Source: Ensembl
  • liver regeneration Source: RGD
  • translation Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L19
Gene namesi
Name:Rpl19
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi621183 Rpl19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001311721 – 19660S ribosomal protein L19Add BLAST196

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei5CitrullineBy similarity1
Modified residuei13PhosphoserineBy similarity1
Modified residuei16CitrullineBy similarity1
Modified residuei38CitrullineBy similarity1
Modified residuei164PhosphoserineBy similarity1
Cross-linki181Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)By similarity
Modified residuei187PhosphothreonineBy similarity1

Post-translational modificationi

Citrullinated by PADI4.By similarity

Keywords - PTMi

Citrullination, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiP84100
PRIDEiP84100

PTM databases

iPTMnetiP84100
PhosphoSitePlusiP84100

Expressioni

Gene expression databases

BgeeiENSRNOG00000004741
GenevisibleiP84100 RN

Interactioni

Protein-protein interaction databases

BioGridi249639, 2 interactors
IntActiP84100, 1 interactor
STRINGi10116.ENSRNOP00000006359

Structurei

3D structure databases

ProteinModelPortaliP84100
SMRiP84100
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1696 Eukaryota
COG2147 LUCA
GeneTreeiENSGT00390000012628
HOGENOMiHOG000231277
HOVERGENiHBG056059
InParanoidiP84100
KOiK02885
OMAiNRVWIDP
OrthoDBiEOG091G0MKY
PhylomeDBiP84100
TreeFamiTF313598

Family and domain databases

CDDicd01417 Ribosomal_L19e_E, 1 hit
Gene3Di1.10.1650.10, 1 hit
HAMAPiMF_01475 Ribosomal_L19e, 1 hit
InterProiView protein in InterPro
IPR035970 60S_ribosomal_L19/L19e_sf
IPR000196 Ribosomal_L19/L19e
IPR023638 Ribosomal_L19/L19e_CS
IPR015972 Ribosomal_L19/L19e_dom1
IPR033935 Ribosomal_L19_euka
PfamiView protein in Pfam
PF01280 Ribosomal_L19e, 1 hit
SMARTiView protein in SMART
SM01416 Ribosomal_L19e, 1 hit
SUPFAMiSSF48140 SSF48140, 1 hit
PROSITEiView protein in PROSITE
PS00526 RIBOSOMAL_L19E, 1 hit

Sequencei

Sequence statusi: Complete.

P84100-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI
60 70 80 90 100
IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARMP EKVTWMRRMR
110 120 130 140 150
ILRRLLRRYR ESKKIDRHMY HSLYLKVKGN VFKNKRILME HIHKLKADKA
160 170 180 190
RKKLLADQAE ARRSKTKEAR KRREERLQAK KEEIIKTLSK EEETKK
Length:196
Mass (Da):23,466
Last modified:August 16, 2004 - v1
Checksum:i4AF506393E526216
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02650 mRNA Translation: AAA42071.1
X82202 Genomic DNA Translation: CAA57685.1
BC058135 mRNA Translation: AAH58135.1
PIRiA26710 R5RT19
RefSeqiNP_112365.1, NM_031103.1
UniGeneiRn.3384

Genome annotation databases

EnsembliENSRNOT00000006359; ENSRNOP00000006359; ENSRNOG00000004741
GeneIDi81767
KEGGirno:81767
UCSCiRGD:621183 rat

Similar proteinsi

Entry informationi

Entry nameiRL19_RAT
AccessioniPrimary (citable) accession number: P84100
Secondary accession number(s): P14118, P22908
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: April 25, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health