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P84099 (RL19_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L19
Gene names
Name:Rpl19
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length196 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Post-translational modification

Citrullinated by PADI4. HAMAP-Rule MF_01475

Sequence similarities

Belongs to the ribosomal protein L19e family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 19619660S ribosomal protein L19 HAMAP-Rule MF_01475
PRO_0000131171

Amino acid modifications

Modified residue51Citrulline HAMAP-Rule MF_01475
Modified residue131Phosphoserine By similarity
Modified residue161Citrulline HAMAP-Rule MF_01475
Modified residue381Citrulline HAMAP-Rule MF_01475
Modified residue1871Phosphothreonine By similarity

Experimental info

Sequence conflict1791A → S in AAB48630. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P84099 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 4AF506393E526216

FASTA19623,466
        10         20         30         40         50         60 
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR 

        70         80         90        100        110        120 
ARCRKNTLAR RKGRHMGIGK RKGTANARMP EKVTWMRRMR ILRRLLRRYR ESKKIDRHMY 

       130        140        150        160        170        180 
HSLYLKVKGN VFKNKRILME HIHKLKADKA RKKLLADQAE ARRSKTKEAR KRREERLQAK 

       190 
KEEIIKTLSK EEETKK 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence of mouse L19 ribosomal protein cDNA isolated in screening with tre oncogene probes."
Nakamura T., Onno M., Mariage-Samson R., Hillova J., Hill M.
DNA Cell Biol. 9:697-703(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[4]Lubec G., Sunyer B., Chen W.-Q.
Submitted (JAN-2009) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 187-195, IDENTIFICATION BY MASS SPECTROMETRY.
Strain: OF1.
Tissue: Hippocampus.
[5]"Citrullination regulates pluripotency and histone H1 binding to chromatin."
Christophorou M.A., Castelo-Branco G., Halley-Stott R.P., Oliveira C.S., Loos R., Radzisheuskaya A., Mowen K.A., Bertone P., Silva J.C., Zernicka-Goetz M., Nielsen M.L., Gurdon J.B., Kouzarides T.
Nature 0:0-0(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: CITRULLINATION AT ARG-5; ARG-16 AND ARG-38.
[6]"Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation."
He X., Tabaczewski P., Ho J., Stroynowski I., Garcia K.C.
Structure 9:1213-1224(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 137-145 IN COMPLEX WITH MHC.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M62952 mRNA. Translation: AAB48630.1.
AK010440 mRNA. Translation: BAB26941.1.
BC010710 mRNA. Translation: AAH10710.1.
BC083131 mRNA. Translation: AAH83131.1.
PIRA36554.
RefSeqNP_033104.2. NM_009078.2.
UniGeneMm.10247.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1K8DX-ray2.30P137-145[»]
ProteinModelPortalP84099.
SMRP84099. Positions 1-189.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid202969. 8 interactions.
IntActP84099. 6 interactions.
MINTMINT-1864295.

PTM databases

PhosphoSiteP84099.

Proteomic databases

PaxDbP84099.
PRIDEP84099.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000017548; ENSMUSP00000017548; ENSMUSG00000017404.
GeneID19921.
KEGGmmu:19921.
UCSCuc007lfj.2. mouse.

Organism-specific databases

CTD6143.
MGIMGI:98020. Rpl19.

Phylogenomic databases

eggNOGCOG2147.
HOGENOMHOG000231277.
HOVERGENHBG056059.
InParanoidP84099.
KOK02885.
OMAYRDAGKI.
PhylomeDBP84099.
TreeFamTF313598.

Gene expression databases

BgeeP84099.
CleanExMM_RPL19.
GenevestigatorP84099.

Family and domain databases

Gene3D1.10.1200.60. 1 hit.
1.10.1650.10. 1 hit.
HAMAPMF_01475. Ribosomal_L19e.
InterProIPR027547. Ribosomal_L19/L19e.
IPR023638. Ribosomal_L19/L19e_CS.
IPR000196. Ribosomal_L19/L19e_dom.
IPR015972. Ribosomal_L19/L19e_dom1.
IPR015974. Ribosomal_L19/L19e_dom3.
[Graphical view]
PfamPF01280. Ribosomal_L19e. 1 hit.
[Graphical view]
SUPFAMSSF48140. SSF48140. 1 hit.
PROSITEPS00526. RIBOSOMAL_L19E. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSRPL19. mouse.
EvolutionaryTraceP84099.
NextBio23865.
PROP84099.
SOURCESearch...

Entry information

Entry nameRL19_MOUSE
AccessionPrimary (citable) accession number: P84099
Secondary accession number(s): P14118, P22908
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: April 16, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot