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Protein

Histone H4

Gene

His4

more
Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi17 – 215

GO - Molecular functioni

  • DNA binding Source: UniProtKB

GO - Biological processi

  • centrosome duplication Source: FlyBase
  • chromatin assembly or disassembly Source: FlyBase
  • DNA-templated transcription, initiation Source: InterPro
  • female meiosis chromosome segregation Source: FlyBase
  • nucleosome assembly Source: UniProtKB
Complete GO annotation...

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

ReactomeiR-DME-212300. PRC2 methylates histones and DNA.
R-DME-2559580. Oxidative Stress Induced Senescence.
R-DME-2559582. Senescence-Associated Secretory Phenotype (SASP).
R-DME-3214841. PKMTs methylate histone lysines.
R-DME-3214842. HDMs demethylate histones.
R-DME-3214847. HATs acetylate histones.
R-DME-3214858. RMTs methylate histone arginines.
R-DME-427359. SIRT1 negatively regulates rRNA Expression.
R-DME-427413. NoRC negatively regulates rRNA expression.
R-DME-5578749. Transcriptional regulation by small RNAs.
R-DME-5693565. Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks.
R-DME-73777. RNA Polymerase I Chain Elongation.

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H4
Gene namesi
Name:His4
Synonyms:H4
AND
Name:His4r
Synonyms:H4r
ORF Names:CG3379
AND
ORF Names:CG31611
AND
ORF Names:CG33869
AND
ORF Names:CG33871
AND
ORF Names:CG33873
AND
ORF Names:CG33875
AND
ORF Names:CG33877
AND
ORF Names:CG33879
AND
ORF Names:CG33881
AND
ORF Names:CG33883
AND
ORF Names:CG33885
AND
ORF Names:CG33887
AND
ORF Names:CG33889
AND
ORF Names:CG33891
AND
ORF Names:CG33893
AND
ORF Names:CG33895
AND
ORF Names:CG33897
AND
ORF Names:CG33899
AND
ORF Names:CG33901
AND
ORF Names:CG33903
AND
ORF Names:CG33905
AND
ORF Names:CG33907
AND
ORF Names:CG33909
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componentsi: Chromosome 2L, Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0001200. His4.
FBgn0051611. His4:CG31611.
FBgn0053869. His4:CG33869.
FBgn0053871. His4:CG33871.
FBgn0053873. His4:CG33873.
FBgn0053875. His4:CG33875.
FBgn0053877. His4:CG33877.
FBgn0053879. His4:CG33879.
FBgn0053881. His4:CG33881.
FBgn0053883. His4:CG33883.
FBgn0053885. His4:CG33885.
FBgn0053887. His4:CG33887.
FBgn0053889. His4:CG33889.
FBgn0053891. His4:CG33891.
FBgn0053893. His4:CG33893.
FBgn0053895. His4:CG33895.
FBgn0053897. His4:CG33897.
FBgn0053899. His4:CG33899.
FBgn0053901. His4:CG33901.
FBgn0053903. His4:CG33903.
FBgn0053905. His4:CG33905.
FBgn0053907. His4:CG33907.
FBgn0053909. His4:CG33909.
FBgn0013981. His4r.

Subcellular locationi

GO - Cellular componenti

  • chromosome Source: FlyBase
  • lipid particle Source: FlyBase
  • nuclear chromosome Source: FlyBase
  • nucleosome Source: UniProtKB
  • RCAF complex Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

Chromosome, Nucleosome core, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001583052 – 103Histone H4Add BLAST102

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei6N6-acetyllysine1 Publication1
Modified residuei13N6-acetyllysine1 Publication1
Modified residuei81Phosphothreonine1 Publication1
Modified residuei83Phosphothreonine1 Publication1

Post-translational modificationi

Acetylated on Lys-6 and Lys-13 during prophase I of meiosis. Phosphorylation of H2A 'Thr-119' is a prerequisite for H4 Lys-6 acetylation but not for H4 Lys-13 acetylation.2 Publications

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiP84040.
PRIDEiP84040.

PTM databases

iPTMnetiP84040.

Expressioni

Gene expression databases

BgeeiFBgn0013981.
ExpressionAtlasiP84040. baseline.
GenevisibleiP84040. DM.

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

Binary interactionsi

WithEntry#Exp.IntActNotes
KAT2BQ928312EBI-185028,EBI-477430From a different organism.

Protein-protein interaction databases

BioGridi534263. 1 interactor.
66847. 11 interactors.
77139. 8 interactors.
DIPiDIP-29505N.
IntActiP84040. 28 interactors.
MINTiMINT-836772.
STRINGi7227.FBpp0091154.

Structurei

Secondary structure

1103
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi26 – 29Combined sources4
Helixi32 – 40Combined sources9
Beta strandi45 – 47Combined sources3
Helixi51 – 76Combined sources26
Beta strandi80 – 82Combined sources3
Helixi84 – 93Combined sources10
Beta strandi98 – 101Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2NQBX-ray2.30B/F2-103[»]
2PYOX-ray2.43B/F2-103[»]
2XYIX-ray1.75B27-46[»]
3C9CX-ray3.20B16-42[»]
4QLCX-ray3.50B/F2-103[»]
4UUZX-ray2.90B1-103[»]
4X23X-ray3.50B/F/L/P25-103[»]
ProteinModelPortaliP84040.
SMRiP84040.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP84040.

Family & Domainsi

Sequence similaritiesi

Belongs to the histone H4 family.Curated

Phylogenomic databases

eggNOGiKOG3467. Eukaryota.
COG2036. LUCA.
GeneTreeiENSGT00760000119019.
InParanoidiP84040.
KOiK11254.
OMAiSTHNERI.
OrthoDBiEOG091G0XGD.
PhylomeDBiP84040.

Family and domain databases

CDDicd00076. H4. 1 hit.
Gene3Di1.10.20.10. 1 hit.
InterProiIPR009072. Histone-fold.
IPR001951. Histone_H4.
IPR019809. Histone_H4_CS.
IPR004823. TAF_TATA-bd.
[Graphical view]
PRINTSiPR00623. HISTONEH4.
SMARTiSM00417. H4. 1 hit.
SM00803. TAF. 1 hit.
[Graphical view]
SUPFAMiSSF47113. SSF47113. 1 hit.
PROSITEiPS00047. HISTONE_H4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P84040-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL
60 70 80 90 100
IYEETRGVLK VFLENVIRDA VTYTEHAKRK TVTAMDVVYA LKRQGRTLYG

FGG
Length:103
Mass (Da):11,381
Last modified:January 23, 2007 - v2
Checksum:iDF3EB26393BD208C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14215 Genomic DNA. Translation: CAA32435.1.
X97437 Genomic DNA. Translation: CAA66067.1.
X97438 mRNA. Translation: CAA66068.1.
AE014297 Genomic DNA. Translation: AAF55080.1.
AE014134 Genomic DNA. Translation: AAN11126.1.
AE014297 Genomic DNA. Translation: AAN13612.1.
AE014297 Genomic DNA. Translation: AAN13613.1.
AE014134 Genomic DNA. Translation: AAZ66480.1.
AE014134 Genomic DNA. Translation: AAZ66484.1.
AE014134 Genomic DNA. Translation: AAZ66489.1.
AE014134 Genomic DNA. Translation: AAZ66493.1.
AE014134 Genomic DNA. Translation: AAZ66498.1.
AE014134 Genomic DNA. Translation: AAZ66503.1.
AE014134 Genomic DNA. Translation: AAZ66508.1.
AE014134 Genomic DNA. Translation: AAZ66513.1.
AE014134 Genomic DNA. Translation: AAZ66518.1.
AE014134 Genomic DNA. Translation: AAZ66523.1.
AE014134 Genomic DNA. Translation: AAZ66528.1.
AE014134 Genomic DNA. Translation: AAZ66533.1.
AE014134 Genomic DNA. Translation: AAZ66538.1.
AE014134 Genomic DNA. Translation: AAZ66543.1.
AE014134 Genomic DNA. Translation: AAZ66548.1.
AE014134 Genomic DNA. Translation: AAZ66553.1.
AE014134 Genomic DNA. Translation: AAZ66558.1.
AE014134 Genomic DNA. Translation: AAZ66563.1.
AE014134 Genomic DNA. Translation: AAZ66568.1.
AE014134 Genomic DNA. Translation: AAZ66573.1.
AE014134 Genomic DNA. Translation: AAZ66578.1.
BT001842 mRNA. Translation: AAN71603.1.
BT015217 mRNA. Translation: AAT94446.1.
PIRiS10098. HSFF4.
RefSeqiNP_001027284.1. NM_001032113.2.
NP_001027288.1. NM_001032117.2.
NP_001027293.1. NM_001032122.2.
NP_001027297.1. NM_001032126.2.
NP_001027302.1. NM_001032131.2.
NP_001027307.1. NM_001032136.2.
NP_001027312.1. NM_001032141.2.
NP_001027317.1. NM_001032146.2.
NP_001027322.1. NM_001032151.2.
NP_001027327.1. NM_001032156.2.
NP_001027332.1. NM_001032161.2.
NP_001027337.1. NM_001032166.2.
NP_001027342.1. NM_001032171.2.
NP_001027347.1. NM_001032176.2.
NP_001027352.1. NM_001032181.2.
NP_001027357.1. NM_001032186.2.
NP_001027362.1. NM_001032191.2.
NP_001027367.1. NM_001032196.1.
NP_001027372.1. NM_001032201.1.
NP_001027377.1. NM_001032206.1.
NP_001027382.1. NM_001032211.1.
NP_001262576.1. NM_001275647.1.
NP_524352.1. NM_079628.4.
NP_724344.1. NM_165383.3.
NP_731927.1. NM_169592.3.
NP_731928.1. NM_169593.3.
UniGeneiDm.29514.
Dm.30223.
Dm.30876.
Dm.5747.

Genome annotation databases

EnsemblMetazoaiFBtr0082962; FBpp0082421; FBgn0013981.
FBtr0082963; FBpp0082422; FBgn0013981.
FBtr0082964; FBpp0082423; FBgn0013981.
FBtr0085926; FBpp0085280; FBgn0051611.
FBtr0091875; FBpp0091116; FBgn0053871.
FBtr0091877; FBpp0091118; FBgn0053873.
FBtr0091879; FBpp0091120; FBgn0053875.
FBtr0091887; FBpp0091128; FBgn0053883.
FBtr0091889; FBpp0091130; FBgn0053885.
FBtr0091891; FBpp0091132; FBgn0053887.
FBtr0091893; FBpp0091134; FBgn0053889.
FBtr0091895; FBpp0091136; FBgn0053891.
FBtr0091897; FBpp0091138; FBgn0053893.
FBtr0091899; FBpp0091140; FBgn0053895.
FBtr0091901; FBpp0091142; FBgn0053897.
FBtr0091903; FBpp0091144; FBgn0053899.
FBtr0091905; FBpp0091146; FBgn0053901.
FBtr0091907; FBpp0091148; FBgn0053903.
FBtr0091909; FBpp0091150; FBgn0053905.
FBtr0091911; FBpp0091152; FBgn0053907.
FBtr0091913; FBpp0091154; FBgn0053909.
FBtr0334029; FBpp0306146; FBgn0013981.
GeneIDi318846.
3771854.
3771893.
3771908.
3771935.
3771938.
3771941.
3771947.
3772096.
3772113.
3772129.
3772172.
3772211.
3772254.
3772314.
3772317.
3772319.
3772325.
3772509.
3772519.
3772666.
3772708.
41773.
KEGGidme:Dmel_CG31611.
dme:Dmel_CG3379.
dme:Dmel_CG33869.
dme:Dmel_CG33871.
dme:Dmel_CG33873.
dme:Dmel_CG33875.
dme:Dmel_CG33877.
dme:Dmel_CG33879.
dme:Dmel_CG33881.
dme:Dmel_CG33883.
dme:Dmel_CG33885.
dme:Dmel_CG33887.
dme:Dmel_CG33889.
dme:Dmel_CG33891.
dme:Dmel_CG33893.
dme:Dmel_CG33895.
dme:Dmel_CG33897.
dme:Dmel_CG33899.
dme:Dmel_CG33901.
dme:Dmel_CG33903.
dme:Dmel_CG33905.
dme:Dmel_CG33907.
dme:Dmel_CG33909.
UCSCiCG31611-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14215 Genomic DNA. Translation: CAA32435.1.
X97437 Genomic DNA. Translation: CAA66067.1.
X97438 mRNA. Translation: CAA66068.1.
AE014297 Genomic DNA. Translation: AAF55080.1.
AE014134 Genomic DNA. Translation: AAN11126.1.
AE014297 Genomic DNA. Translation: AAN13612.1.
AE014297 Genomic DNA. Translation: AAN13613.1.
AE014134 Genomic DNA. Translation: AAZ66480.1.
AE014134 Genomic DNA. Translation: AAZ66484.1.
AE014134 Genomic DNA. Translation: AAZ66489.1.
AE014134 Genomic DNA. Translation: AAZ66493.1.
AE014134 Genomic DNA. Translation: AAZ66498.1.
AE014134 Genomic DNA. Translation: AAZ66503.1.
AE014134 Genomic DNA. Translation: AAZ66508.1.
AE014134 Genomic DNA. Translation: AAZ66513.1.
AE014134 Genomic DNA. Translation: AAZ66518.1.
AE014134 Genomic DNA. Translation: AAZ66523.1.
AE014134 Genomic DNA. Translation: AAZ66528.1.
AE014134 Genomic DNA. Translation: AAZ66533.1.
AE014134 Genomic DNA. Translation: AAZ66538.1.
AE014134 Genomic DNA. Translation: AAZ66543.1.
AE014134 Genomic DNA. Translation: AAZ66548.1.
AE014134 Genomic DNA. Translation: AAZ66553.1.
AE014134 Genomic DNA. Translation: AAZ66558.1.
AE014134 Genomic DNA. Translation: AAZ66563.1.
AE014134 Genomic DNA. Translation: AAZ66568.1.
AE014134 Genomic DNA. Translation: AAZ66573.1.
AE014134 Genomic DNA. Translation: AAZ66578.1.
BT001842 mRNA. Translation: AAN71603.1.
BT015217 mRNA. Translation: AAT94446.1.
PIRiS10098. HSFF4.
RefSeqiNP_001027284.1. NM_001032113.2.
NP_001027288.1. NM_001032117.2.
NP_001027293.1. NM_001032122.2.
NP_001027297.1. NM_001032126.2.
NP_001027302.1. NM_001032131.2.
NP_001027307.1. NM_001032136.2.
NP_001027312.1. NM_001032141.2.
NP_001027317.1. NM_001032146.2.
NP_001027322.1. NM_001032151.2.
NP_001027327.1. NM_001032156.2.
NP_001027332.1. NM_001032161.2.
NP_001027337.1. NM_001032166.2.
NP_001027342.1. NM_001032171.2.
NP_001027347.1. NM_001032176.2.
NP_001027352.1. NM_001032181.2.
NP_001027357.1. NM_001032186.2.
NP_001027362.1. NM_001032191.2.
NP_001027367.1. NM_001032196.1.
NP_001027372.1. NM_001032201.1.
NP_001027377.1. NM_001032206.1.
NP_001027382.1. NM_001032211.1.
NP_001262576.1. NM_001275647.1.
NP_524352.1. NM_079628.4.
NP_724344.1. NM_165383.3.
NP_731927.1. NM_169592.3.
NP_731928.1. NM_169593.3.
UniGeneiDm.29514.
Dm.30223.
Dm.30876.
Dm.5747.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2NQBX-ray2.30B/F2-103[»]
2PYOX-ray2.43B/F2-103[»]
2XYIX-ray1.75B27-46[»]
3C9CX-ray3.20B16-42[»]
4QLCX-ray3.50B/F2-103[»]
4UUZX-ray2.90B1-103[»]
4X23X-ray3.50B/F/L/P25-103[»]
ProteinModelPortaliP84040.
SMRiP84040.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi534263. 1 interactor.
66847. 11 interactors.
77139. 8 interactors.
DIPiDIP-29505N.
IntActiP84040. 28 interactors.
MINTiMINT-836772.
STRINGi7227.FBpp0091154.

PTM databases

iPTMnetiP84040.

Proteomic databases

PaxDbiP84040.
PRIDEiP84040.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0082962; FBpp0082421; FBgn0013981.
FBtr0082963; FBpp0082422; FBgn0013981.
FBtr0082964; FBpp0082423; FBgn0013981.
FBtr0085926; FBpp0085280; FBgn0051611.
FBtr0091875; FBpp0091116; FBgn0053871.
FBtr0091877; FBpp0091118; FBgn0053873.
FBtr0091879; FBpp0091120; FBgn0053875.
FBtr0091887; FBpp0091128; FBgn0053883.
FBtr0091889; FBpp0091130; FBgn0053885.
FBtr0091891; FBpp0091132; FBgn0053887.
FBtr0091893; FBpp0091134; FBgn0053889.
FBtr0091895; FBpp0091136; FBgn0053891.
FBtr0091897; FBpp0091138; FBgn0053893.
FBtr0091899; FBpp0091140; FBgn0053895.
FBtr0091901; FBpp0091142; FBgn0053897.
FBtr0091903; FBpp0091144; FBgn0053899.
FBtr0091905; FBpp0091146; FBgn0053901.
FBtr0091907; FBpp0091148; FBgn0053903.
FBtr0091909; FBpp0091150; FBgn0053905.
FBtr0091911; FBpp0091152; FBgn0053907.
FBtr0091913; FBpp0091154; FBgn0053909.
FBtr0334029; FBpp0306146; FBgn0013981.
GeneIDi318846.
3771854.
3771893.
3771908.
3771935.
3771938.
3771941.
3771947.
3772096.
3772113.
3772129.
3772172.
3772211.
3772254.
3772314.
3772317.
3772319.
3772325.
3772509.
3772519.
3772666.
3772708.
41773.
KEGGidme:Dmel_CG31611.
dme:Dmel_CG3379.
dme:Dmel_CG33869.
dme:Dmel_CG33871.
dme:Dmel_CG33873.
dme:Dmel_CG33875.
dme:Dmel_CG33877.
dme:Dmel_CG33879.
dme:Dmel_CG33881.
dme:Dmel_CG33883.
dme:Dmel_CG33885.
dme:Dmel_CG33887.
dme:Dmel_CG33889.
dme:Dmel_CG33891.
dme:Dmel_CG33893.
dme:Dmel_CG33895.
dme:Dmel_CG33897.
dme:Dmel_CG33899.
dme:Dmel_CG33901.
dme:Dmel_CG33903.
dme:Dmel_CG33905.
dme:Dmel_CG33907.
dme:Dmel_CG33909.
UCSCiCG31611-RA. d. melanogaster.

Organism-specific databases

CTDi318846.
3771854.
3771893.
3771908.
3771935.
3771938.
3771941.
3771947.
3772096.
3772113.
3772129.
3772172.
3772211.
3772254.
3772314.
3772317.
3772319.
3772325.
3772509.
3772519.
3772666.
3772708.
41773.
FlyBaseiFBgn0001200. His4.
FBgn0051611. His4:CG31611.
FBgn0053869. His4:CG33869.
FBgn0053871. His4:CG33871.
FBgn0053873. His4:CG33873.
FBgn0053875. His4:CG33875.
FBgn0053877. His4:CG33877.
FBgn0053879. His4:CG33879.
FBgn0053881. His4:CG33881.
FBgn0053883. His4:CG33883.
FBgn0053885. His4:CG33885.
FBgn0053887. His4:CG33887.
FBgn0053889. His4:CG33889.
FBgn0053891. His4:CG33891.
FBgn0053893. His4:CG33893.
FBgn0053895. His4:CG33895.
FBgn0053897. His4:CG33897.
FBgn0053899. His4:CG33899.
FBgn0053901. His4:CG33901.
FBgn0053903. His4:CG33903.
FBgn0053905. His4:CG33905.
FBgn0053907. His4:CG33907.
FBgn0053909. His4:CG33909.
FBgn0013981. His4r.

Phylogenomic databases

eggNOGiKOG3467. Eukaryota.
COG2036. LUCA.
GeneTreeiENSGT00760000119019.
InParanoidiP84040.
KOiK11254.
OMAiSTHNERI.
OrthoDBiEOG091G0XGD.
PhylomeDBiP84040.

Enzyme and pathway databases

ReactomeiR-DME-212300. PRC2 methylates histones and DNA.
R-DME-2559580. Oxidative Stress Induced Senescence.
R-DME-2559582. Senescence-Associated Secretory Phenotype (SASP).
R-DME-3214841. PKMTs methylate histone lysines.
R-DME-3214842. HDMs demethylate histones.
R-DME-3214847. HATs acetylate histones.
R-DME-3214858. RMTs methylate histone arginines.
R-DME-427359. SIRT1 negatively regulates rRNA Expression.
R-DME-427413. NoRC negatively regulates rRNA expression.
R-DME-5578749. Transcriptional regulation by small RNAs.
R-DME-5693565. Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks.
R-DME-73777. RNA Polymerase I Chain Elongation.

Miscellaneous databases

ChiTaRSiHis4r. fly.
EvolutionaryTraceiP84040.
PROiP84040.

Gene expression databases

BgeeiFBgn0013981.
ExpressionAtlasiP84040. baseline.
GenevisibleiP84040. DM.

Family and domain databases

CDDicd00076. H4. 1 hit.
Gene3Di1.10.20.10. 1 hit.
InterProiIPR009072. Histone-fold.
IPR001951. Histone_H4.
IPR019809. Histone_H4_CS.
IPR004823. TAF_TATA-bd.
[Graphical view]
PRINTSiPR00623. HISTONEH4.
SMARTiSM00417. H4. 1 hit.
SM00803. TAF. 1 hit.
[Graphical view]
SUPFAMiSSF47113. SSF47113. 1 hit.
PROSITEiPS00047. HISTONE_H4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiH4_DROME
AccessioniPrimary (citable) accession number: P84040
Secondary accession number(s): A4V2W8
, P02307, Q4AB71, Q4ABE0, Q6AWN1, Q9VFH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: November 30, 2016
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.