Reviewed, UniProtKB/Swiss-Prot P83885 (ANIS4_ANISI)

Names and origin

Protein names	Recommended name:     Allergen Ani s 4 Alternative name(s):     Allergen=Ani s 4
Organism	Anisakis simplex (Herring worm)
Taxonomic identifier	6269 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Nematoda › Chromadorea › Ascaridida › Ascaridoidea › Anisakidae › Anisakis › Anisakis simplex complex

Protein attributes

Sequence length	14 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Secreted Ref.1.
Allergenic properties	Causes an allergic reaction in human. Binds to IgE. A.simplex is a fish parasite that, when accidentally ingested by humans, may cause allergic reactions in sensitized individuals. Heat resistant, can cause allergic reactions after heating at 100 degrees Celsius for 30 minutes. Ref.1

Ontologies

Keywords
Cellular component	Secreted
Disease	Allergen
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›14	›14	Allergen Ani s 4		PRO_0000064599
Experimental info
	Non-terminal residue	14	1

Sequences

	Sequence		Length	Mass (Da)
	P83885-1 [UniParc]. Last modified May 10, 2004. Version 1. Checksum: 9EF2289FC9DC51B5	FASTA	14	1,371
	10 GMLGGSSDVD XNXP

References

[1]

"Isolation of a heat-resistant allergen from the fish parasite Anisakis simplex." Moneo I., Caballero M.L., Gonzalez-Munoz M., Rodriguez-Mahillo A.I., Rodriguez-Perez R., Silva A. Parasitol. Res. 96:285-289(2005) [PubMed: 15895253] [Abstract] Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, ALLERGENICITY.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ANIS4_ANISI

Accession

Primary (citable) accession number: P83885

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 24, 2004
Last sequence update:	May 10, 2004
Last modified:	June 16, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)