P83823 (P83823_THETH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Threonine synthase PDB 1UIM PDB 1UIN PDB 1V7C
Organism	Thermus thermophilus PDB 1UIM PDB 1UIN PDB 1V7C
Taxonomic identifier	274 [NCBI]
Taxonomic lineage	Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Pyridoxal phosphate PDB 1UIM PDB 1UIN
Technical term	3D-structure PDB 1UIM PDB 1UIN PDB 1V7C
Gene Ontology (GO)
Biological process	threonine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro threonine synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	61	1	Pyridoxal phosphate PDB 1UIM PDB 1UIN

Sequences

	Sequence		Length	Mass (Da)
	P83823 [UniParc]. Last modified March 15, 2004. Version 1. Checksum: C9F0752976C46CDF	FASTA	351	37,010
	10 20 30 40 50 60 MRPPLIERYR NLLPVSEKTP VISLLEGSTP LIPLKGPEEA RKKGIRLYAK YEGLNPTGSF 70 80 90 100 110 120 KDRGMTLAVS KAVEGGAQAV ACASTGNTAA SAAAYAARAG ILAIVVLPAG YVALGKVAQS 130 140 150 160 170 180 LVHGARIVQV EGNFDDALRL TQKLTEAFPV ALVNSVNPHR LEGQKTLAFE VVDELGDAPH 190 200 210 220 230 240 YHALPVGNAG NITAHWMGYK AYHALGKAKR LPRMLGFQAA GAAPLVLGRP VERPETLATA 250 260 270 280 290 300 IRIGNPASWQ GAVRAKEESG GVIEAVTDEE ILFAYRYLAR EEGIFCEPAS AAAMAGVFKL 310 320 330 340 350 LREGRLEPES TVVLTLTGHG LKDPATAERV AELPPPVPAR LEAVAAAAGL L

References

[1]

"Crystal structures of threonine synthase from Thermus thermophilus HB8: conformational change, substrate recognition, and mechanism." Omi R., Goto M., Miyahara I., Mizuguchi H., Hayashi H., Kagamiyama H., Hirotsu K. J. Biol. Chem. 278:46035-46045(2003) [PubMed: 12952961] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS), PYRIDOXAL PHOSPHATE AT LYS-61.

Cross-references

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1UIM	X-ray	2.15	A/B	1-351	[»]
1UIN	X-ray	2.25	A/B	1-351	[»]
1V7C	X-ray	2.00	A/B/C/D	1-351	[»]

ProteinModelPortal

P83823.

SMR

P83823. Positions 1-351.

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

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Family and domain databases

InterPro

IPR001926. PyrdxlP-dep_enz_bsu.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR004450. Thr_synthase.
[Graphical view]

Pfam

PF00291. PALP. 1 hit.
[Graphical view]

SUPFAM

SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.

TIGRFAMs

TIGR00260. ThrC. 1 hit.

PROSITE

PS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]

ProtoNet

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Entry information

Entry name

P83823_THETH

Accession

Primary (citable) accession number: P83823

Entry history

Integrated into UniProtKB/TrEMBL:	March 15, 2004
Last sequence update:	March 15, 2004
Last modified:	May 31, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)