Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P83763

- CBNB_CUPNE

UniProt

P83763 - CBNB_CUPNE

Protein

Chloromuconate cycloisomerase CbnB

Gene

cbnB

Organism
Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (01 Mar 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.Curated

    Cofactori

    Manganese.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei165 – 1651Proton acceptorBy similarity
    Metal bindingi194 – 1941ManganeseBy similarity
    Metal bindingi220 – 2201ManganeseBy similarity
    Metal bindingi245 – 2451ManganeseBy similarity
    Active sitei323 – 3231Proton donorBy similarity

    GO - Molecular functioni

    1. chloromuconate cycloisomerase activity Source: UniProtKB-EC
    2. manganese ion binding Source: InterPro
    3. muconate cycloisomerase activity Source: InterPro

    GO - Biological processi

    1. aromatic compound catabolic process Source: UniProtKB-KW
    2. cellular amino acid catabolic process Source: InterPro

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Aromatic hydrocarbons catabolism

    Keywords - Ligandi

    Manganese, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00083.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chloromuconate cycloisomerase CbnB (EC:5.5.1.7)
    Alternative name(s):
    Muconate cycloisomerase II CbnB
    Gene namesi
    Name:cbnB1 Publication
    Encoded oniPlasmid pENH910 Publication
    OrganismiCupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
    Taxonomic identifieri106590 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 370370Chloromuconate cycloisomerase CbnBPRO_0000171255Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP83763.
    SMRiP83763. Positions 1-369.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.20.20.120. 1 hit.
    3.30.390.10. 1 hit.
    InterProiIPR013370. Chloromuconate_cycloisomerase.
    IPR029065. Enolase_C-like.
    IPR029017. Enolase_N_like.
    IPR018110. Mandel_Rmase/mucon_lact_enz_CS.
    IPR013342. Mandelate_racemase_C.
    IPR013341. Mandelate_racemase_N.
    IPR001354. MR_MLE.
    [Graphical view]
    PANTHERiPTHR13794. PTHR13794. 1 hit.
    PfamiPF02746. MR_MLE_N. 1 hit.
    [Graphical view]
    SMARTiSM00922. MR_MLE. 1 hit.
    [Graphical view]
    SUPFAMiSSF51604. SSF51604. 1 hit.
    SSF54826. SSF54826. 1 hit.
    TIGRFAMsiTIGR02534. mucon_cyclo. 1 hit.
    PROSITEiPS00908. MR_MLE_1. 1 hit.
    PS00909. MR_MLE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P83763-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKIEAISTTI VDVPTRRPLQ MSFTTVHKQS YVIVQVTAGG LVGIGEGGSV    50
    GGPTWGSESA ETIKVIIDNY LAPLLIGKDA SNLSEARALM DRAVTGNLSA 100
    KAAIDIALHD LKARALNLSI ADLIGGTMRK SIPIAWTLAS GDTARDIDSA 150
    LEMIEARRHN RFKVKLGART PAQDLEHIRS IVKAVGDKAS VRVDVNQGWD 200
    EQTASIWIPR LEEAGVELVE QPVPRANFGA LRRLTEQNGV AILADESLSS 250
    LSSAFELARD RAVDAFSLKL CNMGGIANTL KVAAIAEAAG ISSYGGTMLD 300
    STVGTAAALH VYATLPSLPY GCELIGPWVL SDRLTQQDLE IKDFEVHLPV 350
    GSGLGVDLDH DKVRHYTRAA 370
    Length:370
    Mass (Da):39,465
    Last modified:March 1, 2004 - v1
    Checksum:i195D3101CA18B31C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB019032 Genomic DNA. Translation: BAA74531.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB019032 Genomic DNA. Translation: BAA74531.1 .

    3D structure databases

    ProteinModelPortali P83763.
    SMRi P83763. Positions 1-369.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00083 .

    Family and domain databases

    Gene3Di 3.20.20.120. 1 hit.
    3.30.390.10. 1 hit.
    InterProi IPR013370. Chloromuconate_cycloisomerase.
    IPR029065. Enolase_C-like.
    IPR029017. Enolase_N_like.
    IPR018110. Mandel_Rmase/mucon_lact_enz_CS.
    IPR013342. Mandelate_racemase_C.
    IPR013341. Mandelate_racemase_N.
    IPR001354. MR_MLE.
    [Graphical view ]
    PANTHERi PTHR13794. PTHR13794. 1 hit.
    Pfami PF02746. MR_MLE_N. 1 hit.
    [Graphical view ]
    SMARTi SM00922. MR_MLE. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51604. SSF51604. 1 hit.
    SSF54826. SSF54826. 1 hit.
    TIGRFAMsi TIGR02534. mucon_cyclo. 1 hit.
    PROSITEi PS00908. MR_MLE_1. 1 hit.
    PS00909. MR_MLE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The chlorocatechol-catabolic transposon Tn5707 of Alcaligenes eutrophus NH9, carrying a gene cluster highly homologous to that in the 1,2,4-trichlorobenzene-degrading bacterium Pseudomonas sp. strain P51, confers the ability to grow on 3-chlorobenzoate."
      Ogawa N., Miyashita K.
      Appl. Environ. Microbiol. 65:724-731(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: NH91 Publication.

    Entry informationi

    Entry nameiCBNB_CUPNE
    AccessioniPrimary (citable) accession number: P83763
    Secondary accession number(s): Q93T14, Q9WXC9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: March 1, 2004
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Plasmid

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3