Reviewed, UniProtKB/Swiss-Prot P83731 (RL24_HUMAN)

Names and origin

Protein names

Recommended name:
    60S ribosomal protein L24
Alternative name(s):
    Ribosomal protein L30

Gene names

Name:

RPL24

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	157 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the ribosomal protein L24e family.

Ontologies

Keywords
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational elongation Inferred from Experiment. Source: Reactome
Cellular component	cytosolic large ribosomal subunit Ref.5 Traceable author statement. Source: ProtInc
Molecular function	RNA binding Ref.5 Traceable author statement. Source: ProtInc protein binding Inferred from physical interaction. Source: IntAct structural constituent of ribosome Ref.5 Traceable author statement. Source: ProtInc
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
LSM8	O95777	1	EBI-353146,EBI-347779
LYAR	Q9NX58	1	EBI-353146,EBI-713507
MAGEB2	O15479	1	EBI-353146,EBI-1057615
NDRG1	Q92597	1	EBI-353146,EBI-716486

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 157	157	60S ribosomal protein L24		PRO_0000136867
Amino acid modifications
	Modified residue	83	1	Phosphothreonine Ref.6 Ref.7 Ref.8
	Modified residue	86	1	Phosphoserine Ref.7 Ref.8

Sequences

	Sequence		Length	Mass (Da)
	P83731-1 [UniParc]. Last modified January 16, 2004. Version 1. Checksum: 1D48EEB7C0652574	FASTA	157	17,779
	10 20 30 40 50 60 MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN WTVLYRRKHK 70 80 90 100 110 120 KGQSEEIQKK RTRRAVKFQR AITGASLADI MAKRNQKPEV RKAQREQAIR AAKEAKKAKQ 130 140 150 ASKKTAMAAA KAPTKAAPKQ KIVKPVKVSA PRVGGKR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of cDNA clones encoding the human homologue of Saccharomyces cerevisiae ribosomal protein L30." Johnson K.R. Gene 123:283-285(1993) [PubMed: 8428672] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The human ribosomal protein genes: sequencing and comparative analysis of 73 genes." Yoshihama M., Uechi T., Asakawa S., Kawasaki K., Kato S., Higa S., Maeda N., Minoshima S., Tanaka T., Shimizu N., Kenmochi N. Genome Res. 12:379-390(2002) [PubMed: 11875025] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Colon.
[5]	"A map of 75 human ribosomal protein genes." Kenmochi N., Kawaguchi T., Rozen S., Davis E., Goodman N., Hudson T.J., Tanaka T., Page D.C. Genome Res. 8:509-523(1998) [PubMed: 9582194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 132-157.
[6]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed: 17081983] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-83, MASS SPECTROMETRY. Tissue: Epithelium.
[7]	"Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry." Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A. Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007) [PubMed: 17287340] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-83 AND SER-86, MASS SPECTROMETRY.
[8]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed: 18669648] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-83 AND SER-86, MASS SPECTROMETRY.
[9]	Colinge J., Superti-Furga G., Bennett K.L. Submitted (OCT-2008) to UniProtKB Cited for: IDENTIFICATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M94314 mRNA. Translation: AAC28251.1. AB061828 Genomic DNA. Translation: BAB79466.1. CR456729 mRNA. Translation: CAG33010.1. BC000690 mRNA. Translation: AAH00690.1. BC070193 mRNA. Translation: AAH70193.1. AB007177 Genomic DNA. Translation: BAA25836.1.
IPI	IPI00306332.
PIR	JN0549.
RefSeq	NP_000977.1.
UniGene	Hs.477028 Hs.649475
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P83731. 16 interactions.
PTM databases
PhosphoSite	P83731.
Proteomic databases
PRIDE	P83731.
Genome annotation databases
Ensembl	ENSG00000114391. Homo sapiens. [Contig view]
GeneID	6152.
KEGG	hsa:6152.
UCSC	uc003dvh.1. human.
Organism-specific databases
GeneCards	GC03M102882.
H-InvDB	HIX0003512. HIX0057809.
HGNC	HGNC:10325. RPL24.
MIM	604180. gene.
PharmGKB	PA30954.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	P83731.
HOVERGEN	P83731.
Enzyme and pathway databases
Reactome	REACT_17015. Metabolism of proteins. REACT_1762. 3' -UTR-mediated translational regulation. REACT_6167. Influenza Infection. REACT_71. Gene Expression.
Gene expression databases
ArrayExpress	P83731.
Bgee	P83731.
CleanEx	HS_RPL24.
GermOnline	ENSG00000114391. Homo sapiens.
Family and domain databases
InterPro	IPR000988. Ribosomal_L24e. IPR011017. TRASH. [Graphical view]
Gene3D	G3DSA:2.30.170.20. Ribosomal_L24E. 1 hit.
PANTHER	PTHR10792. Ribosomal_L24E. 1 hit.
Pfam	PF01246. Ribosomal_L24e. 1 hit. [Graphical view]
SMART	SM00746. TRASH. 1 hit. [Graphical view]
PROSITE	PS01073. RIBOSOMAL_L24E. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	23893.
SOURCE	Search...

Entry information

Entry name

RL24_HUMAN

Accession

Primary (citable) accession number: P83731
Secondary accession number(s): P38663, Q6IBS3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	January 16, 2004
Last modified:	July 7, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)