P83731 (RL24_HUMAN) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 98.
History...
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 60S ribosomal protein L24 Alternative name(s): 60S ribosomal protein L30 | ||
| Gene names |
| ||
| Organism | Homo sapiens (Human) [Reference proteome] | ||
| Taxonomic identifier | 9606 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo![]() |
Protein attributes
| Sequence length | 157 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Sequence similarities | Belongs to the ribosomal protein L24e family. |
Ontologies
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| LYAR | Q9NX58 | 1 | EBI-353146,EBI-713507 | |
| MAGEB2 | O15479 | 1 | EBI-353146,EBI-1057615 | |
| NAA38 | O95777 | 1 | EBI-353146,EBI-347779 | |
| NDRG1 | Q92597 | 1 | EBI-353146,EBI-716486 |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 157 | 157 | 60S ribosomal protein L24 | PRO_0000136867 | |||||
Sites | |||||||||
| Site | 1 | 1 | Not acetylated | ||||||
Amino acid modifications | |||||||||
| Modified residue | 27 | 1 | N6-acetyllysine Ref.12 | ||||||
| Modified residue | 77 | 1 | N6-acetyllysine Ref.12 | ||||||
| Modified residue | 83 | 1 | Phosphothreonine Ref.9 Ref.10 | ||||||
| Modified residue | 86 | 1 | Phosphoserine Ref.10 Ref.11 | ||||||
| Modified residue | 93 | 1 | N6-acetyllysine Ref.12 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Characterization of cDNA clones encoding the human homologue of Saccharomyces cerevisiae ribosomal protein L30." Johnson K.R. Gene 123:283-285(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [2] | "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes." Yoshihama M., Uechi T., Asakawa S., Kawasaki K., Kato S., Higa S., Maeda N., Minoshima S., Tanaka T., Shimizu N., Kenmochi N. Genome Res. 12:379-390(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [3] | "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
| [4] | "Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Thymus. |
| [5] | Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. Venter J.C.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [6] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Colon. |
| [7] | Bienvenut W.V., Bilsland A.E., Keith W.N. Submitted (JAN-2010) to UniProtKB Cited for: PROTEIN SEQUENCE OF 1-12; 28-44; 48-56 AND 81-93, LACK OF N-TERMINAL ACETYLATION, MASS SPECTROMETRY. Tissue: Colon carcinoma. |
| [8] | "A map of 75 human ribosomal protein genes." Kenmochi N., Kawaguchi T., Rozen S., Davis E., Goodman N., Hudson T.J., Tanaka T., Page D.C. Genome Res. 8:509-523(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 132-157. |
| [9] | "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-83, MASS SPECTROMETRY. Tissue: Cervix carcinoma. |
| [10] | "A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-83 AND SER-86, MASS SPECTROMETRY. Tissue: Cervix carcinoma. |
| [11] | "Large-scale proteomics analysis of the human kinome." Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G., Mann M., Daub H. Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-86, MASS SPECTROMETRY. |
| [12] | "Lysine acetylation targets protein complexes and co-regulates major cellular functions." Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M. Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-27; LYS-77 AND LYS-93, MASS SPECTROMETRY. |
| [13] | "Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | M94314 mRNA. Translation: AAC28251.1. AB061828 Genomic DNA. Translation: BAB79466.1. CR456729 mRNA. Translation: CAG33010.1. AK311992 mRNA. Translation: BAG34930.1. CH471052 Genomic DNA. Translation: EAW79780.1. BC000690 mRNA. Translation: AAH00690.1. BC070193 mRNA. Translation: AAH70193.1. AB007177 Genomic DNA. Translation: BAA25836.1. |
| IPI | IPI00306332. |
| PIR | JN0549. |
| RefSeq | NP_000977.1. NM_000986.3. |
| UniGene | Hs.477028. Hs.649475. |
3D structure databases | |
| ProteinModelPortal | P83731. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P83731. 17 interactions. |
| MINT | MINT-5000278. |
| STRING | 9606.ENSP00000377640. |
PTM databases | |
| PhosphoSite | P83731. |
Polymorphism databases | |
| DMDM | 41393532. |
Proteomic databases | |
| PaxDb | P83731. |
| PRIDE | P83731. |
Protocols and materials databases | |
| DNASU | 6152. |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENST00000394077; ENSP00000377640; ENSG00000114391. |
| GeneID | 6152. |
| KEGG | hsa:6152. |
| UCSC | uc003dvh.1. human. |
Organism-specific databases | |
| CTD | 6152. |
| GeneCards | GC03M101399. |
| HGNC | HGNC:10325. RPL24. |
| MIM | 604180. gene. |
| neXtProt | NX_P83731. |
| PharmGKB | PA34701. |
| GenAtlas | Search... |
Phylogenomic databases | |
| eggNOG | COG2075. |
| HOGENOM | HOG000184343. |
| HOVERGEN | HBG001066. |
| InParanoid | P83731. |
| KO | K02896. |
| OMA | IHPGHGK. |
| OrthoDB | EOG46DM48. |
| PhylomeDB | P83731. |
Enzyme and pathway databases | |
| Reactome | REACT_116125. Disease. REACT_17015. Metabolism of proteins. REACT_1762. 3' -UTR-mediated translational regulation. REACT_21257. Metabolism of RNA. REACT_71. Gene Expression. |
Gene expression databases | |
| ArrayExpress | P83731. |
| Bgee | P83731. |
| CleanEx | HS_RPL24. |
| Genevestigator | P83731. |
| GermOnline | ENSG00000114391. Homo sapiens. |
Family and domain databases | |
| Gene3D | 2.30.170.20. 1 hit. |
| InterPro | IPR023442. Ribosomal_L24e_CS. IPR023441. Ribosomal_L24e_dom. IPR000988. Ribosomal_L24e_rel. IPR011017. TRASH_dom. [Graphical view] |
| PANTHER | PTHR10792. PTHR10792. 1 hit. |
| Pfam | PF01246. Ribosomal_L24e. 1 hit. [Graphical view] |
| SMART | SM00746. TRASH. 1 hit. [Graphical view] |
| PROSITE | PS01073. RIBOSOMAL_L24E. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| ChiTaRS | RPL24. human. |
| GenomeRNAi | 6152. |
| NextBio | 23893. |
| SOURCE | Search... |
Entry information
| Entry name | RL24_HUMAN | ||||||||
| Accession | Primary (citable) accession number: P83731 Secondary accession number(s): B2R4Y3, P38663, Q6IBS3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
Relevant documents
| Ribosomal proteins Ribosomal proteins families and list of entries |
| Human chromosome 3 Human chromosome 3: entries, gene names and cross-references to MIM |
| MIM cross-references Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |

Clusters with
