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P83726

- IDHC_NAEFO

UniProt

P83726 - IDHC_NAEFO

Protein

Isocitrate dehydrogenase [NADP]

Gene
N/A
Organism
Naegleria fowleri (Brain eating amoeba)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.By similarity

    Cofactori

    Manganese or magnesium.By similarity

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC

    GO - Biological processi

    1. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Tricarboxylic acid cycle

    Keywords - Ligandi

    Magnesium, Manganese, NADP

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP] (EC:1.1.1.42)
    Short name:
    IDH
    Alternative name(s):
    IDP
    NADP(+)-specific ICDH
    NF033
    Oxalosuccinate decarboxylase
    OrganismiNaegleria fowleri (Brain eating amoeba)Curated
    Taxonomic identifieri5763 [NCBI]
    Taxonomic lineageiEukaryotaHeteroloboseaSchizopyrenidaVahlkampfiidaeNaegleria

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – ›20›20Isocitrate dehydrogenase [NADP]PRO_0000083582Add
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Sequencei

    Sequence statusi: Fragment.

    P83726-1 [UniParc]FASTAAdd to Basket

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    AXFQKIKVAN PVVELDGDEM                                    20
    Length:20
    Mass (Da):2,215
    Last modified:January 16, 2004 - v1
    Checksum:i4A8244E9BA01D677
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei20 – 201Curated

    Cross-referencesi

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Comparative study of protein profiles on pathogenic and nonpathogenic Naegleria species by 2D-PAGE."
      Omura M., Furushima-Shimogawara R., Izumiyama S., Endo T.
      Submitted (DEC-2003) to UniProtKB
      Cited for: PROTEIN SEQUENCE.
      Strain: Nf 66.

    Entry informationi

    Entry nameiIDHC_NAEFO
    AccessioniPrimary (citable) accession number: P83726
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 16, 2004
    Last sequence update: January 16, 2004
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Miscellaneous

    On the 2D-gel the determined pI of this protein is: 6.8, its MW is: 32.3 kDa.Curated

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3