P83708 (ODO2_DELAC) Reviewed, UniProtKB/Swiss-Prot
Last modified March 19, 2014. Version 39. History...
Names and origin
|Protein names||Recommended name:|
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex
2-oxoglutarate dehydrogenase complex component E2
Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex
|Organism||Delftia acidovorans (Pseudomonas acidovorans) (Comamonas acidovorans)|
|Taxonomic identifier||80866 [NCBI]|
|Taxonomic lineage||Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Delftia|
|Sequence length||12 AA.|
|Protein existence||Evidence at protein level|
General annotation (Comments)
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity. UniProtKB P52993
Succinyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-succinyldihydrolipoyl)lysine.
Binds 1 lipoyl cofactor covalently By similarity.
Forms a 24-polypeptide structural core with octahedral symmetry By similarity. UniProtKB P52993
By 2,4-dichlorophenol. Ref.1
Belongs to the 2-oxoacid dehydrogenase family.
Contains 1 lipoyl-binding domain.
|Biological process||Tricarboxylic acid cycle|
|Technical term||Direct protein sequencing|
|Gene Ontology (GO)|
|Biological_process||L-lysine catabolic process to acetyl-CoA via saccharopine|
Inferred from electronic annotation. Source: UniProtKB-UniPathwaytricarboxylic acid cycle
Inferred from electronic annotation. Source: UniProtKB-KW
|Molecular_function||dihydrolipoyllysine-residue succinyltransferase activity|
Inferred from electronic annotation. Source: UniProtKB-EC
|Complete GO annotation...|
Sequence annotation (Features)
|Accession||Primary (citable) accession number: P83708|
|Entry status||Reviewed (UniProtKB/Swiss-Prot)|
|Annotation program||Prokaryotic Protein Annotation Program|