Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Kunitz-type serine protease inhibitor DrTI

Gene
N/A
Organism
Delonix regia (Royal poinciana) (Poinciana regia)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Inhibits bovine trypsin and human plasma kallikrein.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei68 – 69Reactive bondSequence analysis2

GO - Molecular functioni

  • serine-type endopeptidase inhibitor activity Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Kunitz-type serine protease inhibitor DrTI
OrganismiDelonix regia (Royal poinciana) (Poinciana regia)Curated
Taxonomic identifieri72433 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaeCaesalpinioideaeCaesalpinieaeDelonix

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000833241 – 185Kunitz-type serine protease inhibitor DrTIAdd BLAST185

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi44 ↔ 89By similarity
Disulfide bondi139 ↔ 147By similarity

Keywords - PTMi

Disulfide bond

Structurei

Secondary structure

1185
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi18 – 24Combined sources7
Beta strandi28 – 30Combined sources3
Beta strandi33 – 37Combined sources5
Beta strandi47 – 50Combined sources4
Beta strandi61 – 64Combined sources4
Beta strandi69 – 72Combined sources4
Beta strandi79 – 85Combined sources7
Beta strandi94 – 98Combined sources5
Beta strandi100 – 103Combined sources4
Beta strandi105 – 108Combined sources4
Turni111 – 113Combined sources3
Helixi116 – 118Combined sources3
Beta strandi122 – 128Combined sources7
Beta strandi130 – 132Combined sources3
Beta strandi134 – 143Combined sources10
Beta strandi148 – 153Combined sources6
Beta strandi155 – 157Combined sources3
Beta strandi159 – 162Combined sources4
Beta strandi164 – 167Combined sources4
Beta strandi172 – 175Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1R8NX-ray1.75A1-185[»]
ProteinModelPortaliP83667.
SMRiP83667.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP83667.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

CDDicd00178. STI. 1 hit.
InterProiIPR011065. Kunitz_inhibitor_ST1-like.
IPR002160. Prot_inh_Kunz-lg.
[Graphical view]
PfamiPF00197. Kunitz_legume. 1 hit.
[Graphical view]
PRINTSiPR00291. KUNITZINHBTR.
SMARTiSM00452. STI. 1 hit.
[Graphical view]
SUPFAMiSSF50386. SSF50386. 1 hit.

Sequencei

Sequence statusi: Complete.

P83667-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SDAEKVYDIE GYPVFLGSEY YIVSAIIGAG GGGVRPGRTR GSMCPMSIIQ
60 70 80 90 100
EQSDLQMGLP VRFSSPEESQ GKIYTDTELE IEFVEKPDCA ESSKWVIVKD
110 120 130 140 150
SGEARVAIGG SEDHPQGELV RGFFKIEKLG SLAYKLVFCP KSSSGSCSDI
160 170 180
GINYEGRRSL VLKSSDDSPF RVVFVKPRSG SETES
Length:185
Mass (Da):20,094
Last modified:December 15, 2003 - v1
Checksum:i55CFF042CC50C7CC
GO

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1R8NX-ray1.75A1-185[»]
ProteinModelPortaliP83667.
SMRiP83667.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP83667.

Family and domain databases

CDDicd00178. STI. 1 hit.
InterProiIPR011065. Kunitz_inhibitor_ST1-like.
IPR002160. Prot_inh_Kunz-lg.
[Graphical view]
PfamiPF00197. Kunitz_legume. 1 hit.
[Graphical view]
PRINTSiPR00291. KUNITZINHBTR.
SMARTiSM00452. STI. 1 hit.
[Graphical view]
SUPFAMiSSF50386. SSF50386. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDRTI_DELRE
AccessioniPrimary (citable) accession number: P83667
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: December 15, 2003
Last modified: November 2, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

The reactive bond has a Glu in position P1 instead of an expected Arg or Lys.Curated

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.