ID   RM40_RAT                Reviewed;         206 AA.
AC   P83565; Q4V8A4;
DT   19-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   24-JAN-2024, entry version 90.
DE   RecName: Full=Large ribosomal subunit protein mL40 {ECO:0000305};
DE   AltName: Full=39S ribosomal protein L40, mitochondrial;
DE            Short=L40mt;
DE            Short=MRP-L40;
DE   Flags: Precursor;
GN   Name=Mrpl40;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116 {ECO:0000305};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 47-75, AND SUBCELLULAR LOCATION.
RX   PubMed=9857009; DOI=10.1074/jbc.273.52.34828;
RA   Goldschmidt-Reisin S., Kitakawa M., Herfurth E., Wittmann-Liebold B.,
RA   Grohmann L., Graack H.-R.;
RT   "Mammalian mitochondrial ribosomal proteins. N-terminal amino acid
RT   sequencing, characterization, and identification of corresponding gene
RT   sequences.";
RL   J. Biol. Chem. 273:34828-34836(1998).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q9NQ50}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:9857009}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mL40 family. {ECO:0000305}.
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DR   EMBL; BC097472; AAH97472.1; -; mRNA.
DR   RefSeq; NP_001020036.1; NM_001024865.1.
DR   AlphaFoldDB; P83565; -.
DR   SMR; P83565; -.
DR   STRING; 10116.ENSRNOP00000065376; -.
DR   PhosphoSitePlus; P83565; -.
DR   jPOST; P83565; -.
DR   PaxDb; 10116-ENSRNOP00000065376; -.
DR   Ensembl; ENSRNOT00000071159.2; ENSRNOP00000065376.1; ENSRNOG00000049686.2.
DR   Ensembl; ENSRNOT00055006091; ENSRNOP00055004613; ENSRNOG00055003853.
DR   Ensembl; ENSRNOT00060021074; ENSRNOP00060016624; ENSRNOG00060012424.
DR   Ensembl; ENSRNOT00065012071; ENSRNOP00065008811; ENSRNOG00065007711.
DR   GeneID; 287962; -.
DR   KEGG; rno:287962; -.
DR   AGR; RGD:1565444; -.
DR   CTD; 64976; -.
DR   RGD; 1565444; Mrpl40.
DR   eggNOG; KOG4778; Eukaryota.
DR   GeneTree; ENSGT00390000010239; -.
DR   HOGENOM; CLU_087493_0_0_1; -.
DR   InParanoid; P83565; -.
DR   OMA; KQREHEM; -.
DR   OrthoDB; 2996073at2759; -.
DR   PhylomeDB; P83565; -.
DR   Reactome; R-RNO-5389840; Mitochondrial translation elongation.
DR   Reactome; R-RNO-5419276; Mitochondrial translation termination.
DR   PRO; PR:P83565; -.
DR   Proteomes; UP000002494; Chromosome 11.
DR   Bgee; ENSRNOG00000049686; Expressed in heart and 20 other cell types or tissues.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005761; C:mitochondrial ribosome; IDA:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; ISO:RGD.
DR   Gene3D; 6.10.250.3440; -; 1.
DR   InterPro; IPR019192; Ribosomal_mL40.
DR   InterPro; IPR039145; Ribosomal_mL40_metazoa/plant.
DR   PANTHER; PTHR13359; 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13359:SF2; 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL; 1.
DR   Pfam; PF09812; MRP-L28; 1.
DR   Genevisible; P83565; RN.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Mitochondrion; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT   TRANSIT         1..46
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000269|PubMed:9857009"
FT   CHAIN           47..206
FT                   /note="Large ribosomal subunit protein mL40"
FT                   /id="PRO_0000087687"
FT   REGION          170..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        56
FT                   /note="V -> Y (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   206 AA;  24397 MW;  500D285FBB8B1E71 CRC64;
     MATAAMLCAA RALRPRSWIP GTCQAQVRHT HQRASLLSFW ELIPMRAEPL RKKKKVDPRK
     DQAAKDRLKK RIRKLERASQ ELVPIEDFIT PVRFLDKSRQ RPQEEHSFEE SERRALLLKR
     WALYKQQEHE MERDAIRAML EAQQEALEQL KLESTELYAE AIKRDTSLFP FEKEGPHYTP
     PVPNYQAPEG RYNDITKVYT QVEFKR
//