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P83542 (PA1_POLGA) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phospholipase A1

EC=3.1.1.32
Alternative name(s):
Allergen=Pol g 1
OrganismPolistes gallicus (Paper wasp)
Taxonomic identifier34730 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataVespoideaVespidaePolistinaePolistiniPolistes

Protein attributes

Sequence length42 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Hydrolysis of phosphatidylcholine with phospholipase A1 (EC 3.1.1.32) activity. Has weak hemolytic activity By similarity.

Catalytic activity

Phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate. Ref.1

Subunit structure

Monomer. Ref.1

Subcellular location

Secreted.

Tissue specificity

Expressed by the venom gland.

Post-translational modification

Contains six disulfide bonds By similarity.

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Belongs to the AB hydrolase superfamily. Lipase family.

Mass spectrometry

Molecular mass is 33475 Da from positions 1 - ?. Determined by ESI. Ref.1

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›42›42Phospholipase A1
PRO_0000090377

Amino acid modifications

Disulfide bond6 ↔ ? By similarity

Experimental info

Non-terminal residue421

Sequences

Sequence LengthMass (Da)Tools
P83542 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 524589208F2113C3

FASTA424,985
        10         20         30         40 
GITPDCTFNE KDIELHVYSR DKRNGIILKK EILKNYDLFK ES 

« Hide

References

[1]"Characterization of the major allergens purified from the venom of the paper wasp Polistes gallicus."
Pantera B., Hoffman D.R., Carresi L., Cappugi G., Turillazzi S., Manao G., Severino M., Spadolini I., Orsomando G., Moneti G., Pazzagli L.
Biochim. Biophys. Acta 1623:72-81(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE, CATALYTIC ACTIVITY, SUBUNIT, MASS SPECTROMETRY.
Tissue: Venom.

Cross-references

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome1208. Pol g 1.
3443. Pol g 1.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry namePA1_POLGA
AccessionPrimary (citable) accession number: P83542
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: June 1, 2003
Last modified: March 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries