P83445 (FRI2_PEA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Ferritin-2, chloroplastic EC=1.16.3.1
Organism	Pisum sativum (Garden pea)
Taxonomic identifier	3888 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Fabeae › Pisum

Protein attributes

Sequence length	13 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation By similarity.
Catalytic activity	4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.
Subunit structure	Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited By similarity.
Subcellular location	Plastid › chloroplast inner membrane. Note: And other plastids. Ref.1
Tissue specificity	Leaves. Ref.1
Miscellaneous	On the 2D-gel the determined pI of this protein is: 4.74, its MW is: 25.7 kDa.
Sequence similarities	Belongs to the ferritin family. UniProtKB P19975

Ontologies

Keywords
Biological process	Iron storage
Cellular component	Chloroplast Membrane Plastid Plastid inner membrane
Ligand	Iron Metal-binding
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	cellular iron ion homeostasis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	chloroplast inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ferroxidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›13	›13	Ferritin-2, chloroplastic		PRO_0000201084
Experimental info
	Non-terminal residue	13	1

Sequences

	Sequence		Length	Mass (Da)
	P83445 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 26C9DC25F334ADC7	FASTA	13	1,246
	10 ATTDSPATLT GVI

References

[1]	Shingles R., McCarty R.E. Submitted (SEP-2002) to UniProtKB Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Strain: cv. Laxton's Progress. Tissue: Leaf.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00540. FERRITIN_1. Partial match. PS00204. FERRITIN_2. Partial match. PS50905. FERRITIN_LIKE. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FRI2_PEA

Accession

Primary (citable) accession number: P83445

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	October 1, 2002
Last modified:	June 28, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program