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Reviewed, UniProtKB/Swiss-Prot P83394 (ITR3_CYCPE)

Last modified July 22, 2008. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Trypsin inhibitor 3
Alternative name(s):
    Trypsin inhibitor III
    CyPTI-III
Cleaved into the following 1 chains:
    1- Recommended name:
            Trypsin inhibitor 1
        Alternative name(s):
            Trypsin inhibitor I
            CyPTI-I
OrganismCyclanthera pedata (Achocha) (Caihua)
Taxonomic identifier198836 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidseurosids ICucurbitalesCucurbitaceaeCyclanthera

Protein attributes

Sequence length29 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Inhibits trypsin.

Subcellular location

Secreted.

Domain

The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin By similarity.

Sequence similarities

Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family. [View classification]

Ontologies

Keywords

   Cellular componentSecreted
   DomainKnottin
   Molecular functionProtease inhibitor
Serine protease inhibitor
   Technical termDirect protein sequencing

Gene Ontology (GO)

None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical view

Molecule processing

Peptide1 – 2929Trypsin inhibitor 3
Peptide2 – 2928Trypsin inhibitor 1

Sites

Site5 – 62Reactive bond

Amino acid modifications

Disulfide bond3 ↔ 20 By similarity
Disulfide bond10 ↔ 22 By similarity
Disulfide bond16 ↔ 28 By similarity

Sequences

Sequence LengthMass (Da)Tools
P83394-1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: D5FEFF8A5FEDCC2F

FASTA293,195
        10         20 
RICPRILMEC KADSDCLAQC ICEESGFCG 

« Hide

References

[1]"Non-conventional affinity chromatography of serine proteinases and their inhibitors."
Polanowski A., Wilimowska-Pelc A., Kowalska J., Grybel J., Zelazko M., Wilusz T.
Acta Biochim. Pol. 50:765-773(2003) [PubMed: 14515156] [Abstract]
Cited for: PROTEIN SEQUENCE, REACTIVE SITE.
Tissue: Seed.

Cross-references

3D structure databases

HSSPHSSP built from PDB template 1CTI based on UniProtKB P01074.
ModBaseSearch...

Family and domain databases

InterProIPR000737. Prot_inh_squash.
[Graphical view]
PfamPF00299. Squash. 1 hit.
[Graphical view]
PRINTSPR00293. SQUASHINHBTR.
ProDomPD003401. Prot_inh_squash. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00286. PTI. 1 hit.
[Graphical view]
PROSITEPS00286. SQUASH_INHIBITOR. 1 hit.
[Graphical view]
BLOCKSSearch...

Other Resources

ProtoNetSearch...

Entry information

Entry nameITR3_CYCPE
AccessionPrimary (citable) accession number: P83394
Secondary accession number(s): P83392
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: October 1, 2002
Last modified: July 22, 2008
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

UniProtKB secondary accession numbers

Index of UniProtKB secondary accession numbers

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents