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P83372

- CISY_FRAAN

UniProt

P83372 - CISY_FRAAN

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Protein

Citrate synthase, mitochondrial

Gene

MCSI

Organism
Fragaria ananassa (Strawberry)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei304 – 3041PROSITE-ProRule annotation
Active sitei350 – 3501PROSITE-ProRule annotation
Active sitei405 – 4051PROSITE-ProRule annotation

GO - Molecular functioni

  1. citrate (Si)-synthase activity Source: InterPro

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00223; UER00717.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthase, mitochondrial (EC:2.3.3.16)
Gene namesi
Name:MCSI
OrganismiFragaria ananassa (Strawberry)Curated
Taxonomic identifieri3747 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesRosaceaeRosoideaePotentilleaeFragariinaeFragaria

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2828Mitochondrion1 PublicationAdd
BLAST
Chaini29 – 469441Citrate synthase, mitochondrialPRO_0000005488Add
BLAST

Proteomic databases

PRIDEiP83372.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP83372.
SMRiP83372. Positions 35-465.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.Curated

Keywords - Domaini

Transit peptide

Family and domain databases

Gene3Di1.10.580.10. 1 hit.
InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR010109. Citrate_synthase_euk.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01793. cit_synth_euk. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P83372 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAFFRTVTKL RSRLGQPPSL RDSVRCLQTQ ASSDLDLHSQ LKELIPEQQE
60 70 80 90 100
RLKKLKKEHG KVQLGTITVD MVIGGMRGMT GLLWETSLLD PDEGIRFRGL
110 120 130 140 150
SIPECQKVLP GATPGGEPLP EGLLWLLLTG KVPSRSKNMH YPVNNGVVPK
160 170 180 190 200
FQIMCSRPLM LCLLEHIPMT QFTTGVMALQ VQSEFQKAYD KGIPKSRYWE
210 220 230 240 250
PTYEDSLSLI AQLPVVASYV YRRIYKGGRM IPVDDSLDYG GNFSHLLGFD
260 270 280 290 300
DHKMQELMRL YVTIHSDHEG GNVSAHTGHL VASALSDPFL SFAAALNGLA
310 320 330 340 350
GPLHGLANQE VLLWIKSVVD ECGENITKDQ LKDYVWKTLN SGKVVPGFGH
360 370 380 390 400
GVLRKTDPRY TCQREFALKH LPDDPLFRLV SKLYDVVPPI LTELGKVKNP
410 420 430 440 450
WPNVDAHSGV LLNHFGLTEA RYFTVLFGVS RSIGIGSQLI WDRALGLPLE
460
RPKSVTMESL ESFCKKAAS
Length:469
Mass (Da):52,283
Last modified:October 1, 2002 - v1
Checksum:iCD80AAED06246F65
GO

Cross-referencesi

3D structure databases

ProteinModelPortali P83372.
SMRi P83372. Positions 35-465.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P83372.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER00717 .

Family and domain databases

Gene3Di 1.10.580.10. 1 hit.
InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR010109. Citrate_synthase_euk.
[Graphical view ]
PANTHERi PTHR11739. PTHR11739. 1 hit.
Pfami PF00285. Citrate_synt. 1 hit.
[Graphical view ]
PRINTSi PR00143. CITRTSNTHASE.
SUPFAMi SSF48256. SSF48256. 1 hit.
TIGRFAMsi TIGR01793. cit_synth_euk. 1 hit.
PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification, cloning and expression analysis of strawberry (Fragaria x ananassa) mitochondrial citrate synthase and mitochondrial malate dehydrogenase."
    Iannetta P.P.M., Escobar N.M., Ross H.A., Souleyre E.J., Hancock R.D., Witte C.P., Davies H.V.
    Physiol. Plantarum 121:15-26(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE, PROTEIN SEQUENCE OF 29-46.
    Strain: cv. Elsanta.
    Tissue: Fruit.

Entry informationi

Entry nameiCISY_FRAAN
AccessioniPrimary (citable) accession number: P83372
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.By similarity

Keywords - Technical termi

Direct protein sequencing

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3