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Protein

Soluble NSF attachment protein 29

Gene

snap-29

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.By similarity

GO - Biological processi

  • intracellular protein transmembrane transport Source: WormBase
  • ovulation Source: WormBase
  • secretion Source: WormBase
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-CEL-6811438. Intra-Golgi traffic.

Protein family/group databases

TCDBi1.F.1.1.3. the synaptosomal vesicle fusion pore (svf-pore) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Soluble NSF attachment protein 29
Gene namesi
Name:snap-29
ORF Names:K02D10.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiK02D10.5; CE17152; WBGene00019305; snap-29.

Subcellular locationi

GO - Cellular componenti

  • apical plasma membrane Source: WormBase
  • cell junction Source: UniProtKB-KW
  • neuron projection Source: UniProtKB-SubCell
  • recycling endosome Source: WormBase
  • synapse Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Synapse, Synaptosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 277277Soluble NSF attachment protein 29PRO_0000213615Add
BLAST

Proteomic databases

EPDiP83351.
PaxDbiP83351.
PRIDEiP83351.

Interactioni

Protein-protein interaction databases

BioGridi41436. 5 interactions.
DIPiDIP-61373N.
STRINGi6239.K02D10.5.

Structurei

3D structure databases

ProteinModelPortaliP83351.
SMRiP83351. Positions 179-243.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini44 – 10663t-SNARE coiled-coil homology 1PROSITE-ProRule annotationAdd
BLAST
Domaini179 – 24163t-SNARE coiled-coil homology 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the SNAP-25 family.Curated
Contains 2 t-SNARE coiled-coil homology domains.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG3065. Eukaryota.
ENOG410Y3Y0. LUCA.
GeneTreeiENSGT00510000048053.
HOGENOMiHOG000018137.
InParanoidiP83351.
KOiK08509.
OMAiRWEAMDN.
OrthoDBiEOG7FNC8G.
PhylomeDBiP83351.

Family and domain databases

InterProiIPR000727. T_SNARE_dom.
[Graphical view]
SMARTiSM00397. t_SNARE. 2 hits.
[Graphical view]
PROSITEiPS50192. T_SNARE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P83351-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRNPFDDDY RPSAASSTMP VKSYTTMGHY SGEDEADYYE REIEKTLQES
60 70 80 90 100
LDSTERSRRH LENSEKIGTS TAQQLLEQRE KLENTEKNLD EIHRTTQMTQ
110 120 130 140 150
RNLNSLKSFF GGMFKNKFTK KPQEPTETPT VPQSKSASRL SETATNLSSG
160 170 180 190 200
GGSATFSGPS GQRTLTESSR SAIKGTRWEA MDNQIDENLD MMSANLRNLQ
210 220 230 240 250
RLGADLGKEV DSQNEMLDRI QYKAERNDGI VRDQDKQMQK ILGTGASTSQ
260 270
TTAESLTPSM DTSTKMSLMM KATSLWK
Length:277
Mass (Da):31,115
Last modified:June 6, 2002 - v1
Checksum:iEF33EBA0ED2574B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081469 Genomic DNA. Translation: CCD71830.1.
RefSeqiNP_498940.1. NM_066539.7.
UniGeneiCel.7443.

Genome annotation databases

EnsemblMetazoaiK02D10.5; K02D10.5; WBGene00019305.
GeneIDi176233.
KEGGicel:CELE_K02D10.5.
UCSCiK02D10.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081469 Genomic DNA. Translation: CCD71830.1.
RefSeqiNP_498940.1. NM_066539.7.
UniGeneiCel.7443.

3D structure databases

ProteinModelPortaliP83351.
SMRiP83351. Positions 179-243.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi41436. 5 interactions.
DIPiDIP-61373N.
STRINGi6239.K02D10.5.

Protein family/group databases

TCDBi1.F.1.1.3. the synaptosomal vesicle fusion pore (svf-pore) family.

Proteomic databases

EPDiP83351.
PaxDbiP83351.
PRIDEiP83351.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK02D10.5; K02D10.5; WBGene00019305.
GeneIDi176233.
KEGGicel:CELE_K02D10.5.
UCSCiK02D10.5. c. elegans.

Organism-specific databases

CTDi176233.
WormBaseiK02D10.5; CE17152; WBGene00019305; snap-29.

Phylogenomic databases

eggNOGiKOG3065. Eukaryota.
ENOG410Y3Y0. LUCA.
GeneTreeiENSGT00510000048053.
HOGENOMiHOG000018137.
InParanoidiP83351.
KOiK08509.
OMAiRWEAMDN.
OrthoDBiEOG7FNC8G.
PhylomeDBiP83351.

Enzyme and pathway databases

ReactomeiR-CEL-6811438. Intra-Golgi traffic.

Miscellaneous databases

PROiP83351.

Family and domain databases

InterProiIPR000727. T_SNARE_dom.
[Graphical view]
SMARTiSM00397. t_SNARE. 2 hits.
[Graphical view]
PROSITEiPS50192. T_SNARE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiSNA29_CAEEL
AccessioniPrimary (citable) accession number: P83351
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: June 6, 2002
Last modified: June 8, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.