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Protein

Soluble NSF attachment protein 29

Gene

snap-29

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.By similarity

GO - Molecular functioni

GO - Biological processi

  • intracellular protein transmembrane transport Source: WormBase
  • ovulation Source: WormBase
  • secretion Source: WormBase
  • synaptic vesicle fusion to presynaptic active zone membrane Source: GO_Central
  • synaptic vesicle priming Source: GO_Central

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

ReactomeiR-CEL-6798695 Neutrophil degranulation
R-CEL-6811438 Intra-Golgi traffic

Protein family/group databases

TCDBi1.F.1.1.3 the synaptosomal vesicle fusion pore (svf-pore) family

Names & Taxonomyi

Protein namesi
Recommended name:
Soluble NSF attachment protein 29
Gene namesi
Name:snap-29
ORF Names:K02D10.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiK02D10.5 ; CE17152 ; WBGene00019305 ; snap-29

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Synapse, Synaptosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002136151 – 277Soluble NSF attachment protein 29Add BLAST277

Proteomic databases

EPDiP83351
PaxDbiP83351
PeptideAtlasiP83351
PRIDEiP83351

Expressioni

Gene expression databases

BgeeiWBGene00019305

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi41436, 5 interactors
DIPiDIP-61373N
IntActiP83351, 1 interactor
STRINGi6239.K02D10.5

Structurei

3D structure databases

ProteinModelPortaliP83351
SMRiP83351
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 106t-SNARE coiled-coil homology 1PROSITE-ProRule annotationAdd BLAST63
Domaini179 – 241t-SNARE coiled-coil homology 2PROSITE-ProRule annotationAdd BLAST63

Sequence similaritiesi

Belongs to the SNAP-25 family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG3065 Eukaryota
ENOG410Y3Y0 LUCA
GeneTreeiENSGT00510000048053
HOGENOMiHOG000018137
InParanoidiP83351
KOiK08509
OMAiQEAQYQA
OrthoDBiEOG091G0GKH
PhylomeDBiP83351

Family and domain databases

InterProiView protein in InterPro
IPR000727 T_SNARE_dom
SMARTiView protein in SMART
SM00397 t_SNARE, 2 hits
PROSITEiView protein in PROSITE
PS50192 T_SNARE, 2 hits

Sequencei

Sequence statusi: Complete.

P83351-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRNPFDDDY RPSAASSTMP VKSYTTMGHY SGEDEADYYE REIEKTLQES
60 70 80 90 100
LDSTERSRRH LENSEKIGTS TAQQLLEQRE KLENTEKNLD EIHRTTQMTQ
110 120 130 140 150
RNLNSLKSFF GGMFKNKFTK KPQEPTETPT VPQSKSASRL SETATNLSSG
160 170 180 190 200
GGSATFSGPS GQRTLTESSR SAIKGTRWEA MDNQIDENLD MMSANLRNLQ
210 220 230 240 250
RLGADLGKEV DSQNEMLDRI QYKAERNDGI VRDQDKQMQK ILGTGASTSQ
260 270
TTAESLTPSM DTSTKMSLMM KATSLWK
Length:277
Mass (Da):31,115
Last modified:June 6, 2002 - v1
Checksum:iEF33EBA0ED2574B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081469 Genomic DNA Translation: CCD71830.1
RefSeqiNP_498940.1, NM_066539.7
UniGeneiCel.7443

Genome annotation databases

EnsemblMetazoaiK02D10.5; K02D10.5; WBGene00019305
GeneIDi176233
KEGGicel:CELE_K02D10.5
UCSCiK02D10.5 c. elegans

Similar proteinsi

Entry informationi

Entry nameiSNA29_CAEEL
AccessioniPrimary (citable) accession number: P83351
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: June 6, 2002
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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