P83348 (TRYP_APIMS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Trypsin EC=3.4.21.4
Organism	Apis mellifera scutellata (Africanized honey bee)
Taxonomic identifier	212527 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Hymenoptera › Apocrita › Aculeata › Apoidea › Apidae › Apinae › Apini › Apis › Apis mellifera

Protein attributes

Sequence length	21 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa. UniProtKB P35004
Subcellular location	Secreted › extracellular space UniProtKB P35004.
Sequence similarities	Belongs to the peptidase S1 family.

Ontologies

Keywords
Biological process	Digestion
Cellular component	Secreted
Molecular function	Hydrolase Protease Serine protease
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	digestion Inferred from electronic annotation. Source: UniProtKB-KW proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	serine-type peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›21	›21	Trypsin		PRO_0000088716
Experimental info
	Non-terminal residue	21	1

Sequences

	Sequence		Length	Mass (Da)
	P83348 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 87F243272932C284	FASTA	21	2,184
	10 20 IVGGTAADIS QFPHQLSLQT T

References

[1]	Takahashi M. Thesis (2002), University of Sao Paulo, Brazil Cited for: PROTEIN SEQUENCE. Strain: Brazilian. Tissue: Midgut.

Cross-references

3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	7460.XP_397087.
Proteomic databases
PaxDb	P83348.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	COG5640.
Family and domain databases
PROSITE	PS00134. TRYPSIN_HIS. Partial match. PS00135. TRYPSIN_SER. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRYP_APIMS

Accession

Primary (citable) accession number: P83348

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	June 1, 2002
Last modified:	April 3, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)